2-Carboxamido-substituted tetracyclines and process for their manufacture

ABSTRACT

2-Carboxamido-substituted tetracyclines of the general formula  A PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THESE COMPOUNDS.

The present invention relates to 2-carboxamido-substituted tetracyclinesof the general formula ##SPC2##

In which R₁ stands for a lower, optionally branched alkyl group, R₂ andR₃ may be identical or different and each stands for hydrogen, anoptionally branched alkyl group of 1 to 6, preferably 1 to 4 carbonatoms, which may carry one or more identical or different groups, suchas a hydroxy group, a lower dialkylamino group, a lower dialkylcarbamoylgroup, a lower alkoxycarbonyl group, a phenyl group, a heterocyclicgroup, especially a 5- or 6-membered ring which may include oxygenand/or nitrogen, and a carboxyl group, in this latter case the alkylmoiety may also be substituted by an amino group, or a cycloalkyl groupof 5 to 7 carbon atoms, and in which R₂ and R₃ may also be closed toform a saturated or unsaturated, 5- or 6-membered ring which may includea nitrogen or oxygen atom and which may carry one or more lower alkylgroups, lower hydroxyalkyl groups, lower carboxyalkyl groups, hydroxylor carboxyl groups, R₄ and R₅ may be identical or different and eachstands for hydrogen or a hydroxy group, R₆ stands for hydrogen or themethyl group, R₅ and R₆ together may also stand for a methylene group,and R₇ stands for a hydrogen, chlorine or bromine atom or for thedimethylamino or diethylamino group, as well as to the physiologicallyacceptable salts thereof.

By lower groups, there are to be understood those containing 1 to 4carbon atoms in the alkyl moiety.

This invention further relates to a process for the manufacture of thesaid compounds, which comprises reacting a tetracycline of the formulaII ##SPC3##

in which R₄ to R₇ are defined as above, with a glyoxylic acid ester ofthe formula III

    o = ch -- co.sub.2 r.sub.1                                 (iii)

or with a semi-acetal thereof corresponding to the formula IV ##EQU1##in which R₁ are defined as above, and R₈ stands for a lower alkyl group,preferably the ethyl group, and with an amine of the formula V

    r.sub.2 -- nh -- r.sub.3                                   (v)

in which R₂ and R₃ are defined as above.

As compounds of formula II, there may be used any tetracyclines havingan unsubstituted 2-carboxamido group, which can be prepared byfermentation or by partial synthesis, for example tetracycline,oxytetracycline, 7-chlorotetracycline, 7-bromotetracycline,7-chloro-6-desmethyl-tetracycline, 6-desmethyl-tetracycline,6-desoxy-5-oxytetracycline,7-dimethylamino-6-desmethyl-6-desoxytetracycline,7-diethylamino-6-desmethyl-6-desoxy-tetracycline,6-methylene-6-desmethyl-6-desoxy-oxytetracycline; preferablytetracycline, oxytetracycline, chlorotetracycline,6-desoxy-5-oxytetracycline and 7-chloro-6-desmethyl-tetracycline.

As amine components of formula V to be used according to the invention,there are mentioned, in addition to ammonia, for example, the followingprimary or secondary aliphatic or heterocyclic amines: methylamine,ethylamine, n-propylamine, i-propylamine, n-butylamine, i-butylamine,pentylamine, hexylamine, dimethylamine, diethylamine, di-n-butylamine,di-i-butylamine, di-i-hexylamine; cyclopentylamine, cyclohexylamine,cycloheptylamine, diethylamino-ethylamine,bis-(diethylaminoethyl)-amine, ethanolamine, diethanol-amine,methyl-hydroxyethylamine, benzylamine, dibenzylamine,β-phenyl-ethylamine, β-phenyl-propylamine, 2-morpholino-ethylamine,2-morpholino-propylamine, 2-piperidino-propylamine,4-morpholino-butylamine, 2-pyrrolidino-ethylamine,dimethylcarbamoyl-ethylamine, glycine ethyl ester, glycine, alanine,leucine, threonine, valine, phenylalanine, aspartic acid, glutamic acid,lysine, ornithine, histidine, proline, hydroxyproline, piperidine,pyrrolidine, piperazine, morpholine, α-methyl-pyrrolidine, α,β- orα,α-dimethyl-pyrrolidine, β-n-propyl-pyrrolidine, N-methyl-piperazine,N-(β-hydroxyethyl)-piperazine and 4carboxy-ethyl-piperidine.

Among the primary and secondary amines of formula V, which have beendisclosed hereinbefore by some typical examples, the secondary amines inwhich R₂ and R₃ stand for alkyl of 1 to 4 carbon atoms, which mayoptionally be substituted by lower alkoxy-carbonyl, carboxyl and,optionally at the same time as carboxyl, also by an amino group, or inwhich R₂ and R₃ may optionally be closed to form a 5- or 6-membered ringwhich may include oxygen or nitrogen and may be substituted, inparticular, by lower alkyl or lower hydroxyalkyl, are preferably usedaccording to the invention.

As examples of the glyoxylic acid esters of formula III, there may bementioned the methyl ester, ethyl ester, propyl ester, i-propyl ester,i-butyl ester, or n-butyl ester, especially the methyl ester, ethylester and n-butyl ester, as well as their semiacetals of formula IV, forexample the methyl-acetal, propyl-acetal or butyl acetal, especially themethyl semi-acetal, ethyl semiacetal and n-butyl semiacetal.

The starting products of formula II and V are products well known in theart, those of formula III can be obtained in simple manner for exampleaccording to "Organic Synthesis Coll." Vol. IV, page 124 (1963). Thestarting compounds of formula IV can be prepared, for example accordingto Organikum, 6th edition 1967, page 352.

The reaction of the invention is carried out, for example by dissolvingor suspending a compound of formula II in a suitable solvent, forexample chloroform, dimethylformamide, methylene chloride, formamide,glycol dimethyl ether, dioxan, tetrahydrofuran, acetone, tetramethylurea or N-methylpyrrolidone, and reacting this solution or suspension attemperatures of about 0° to 100°C, preferably about 20° to 50°C, withstoichiometric amounts or an excess amount of a glyoxylic acidderivative of formula III or IV and stoichiometric amounts or an excessamount of an amine of formula V. If excess amounts of compounds offormula III or IV or V are used, this excess may vary greatly, forexample between 1 and 10 mols.

The compounds of formula III or IV or V may be added directly or insolution. It does not matter in which succession the reaction componentsare mixed together, but it is advantageous first to mix the aminecomponent of formula V with the glyoxylic acid derivative and then toadd the tetracycline component of formula II.

After having been mixed for several hours, where required under an inertgas, the reaction mixture may be concentrated by evaporation in vacuo attemperatures of about 20° to 50°C, and the remaining crude product maybe dissolved preferably in a polar aprotic solvent, for example ethylacetate, butyl acetate, dichloromethane, chloroform, dioxan ortetrahydrofuran. Precipitation with a less polar aprotic solvent, forexample diethyl ether, diisopropyl ether, di-n-butyl ether, benzene,toluene, petrol ether or cyclohexane yields the reaction product in asolid pure form.

As physiologically acceptable salt-forming agents of the products offormula I, there are mentioned, for example, mineral acids, such ashydrochloric acid, sulfuric acid, nitric acid, phosphoric acid or boricacid; and organic acids, such as acetic acid, lactic acid, citric acid,maleic acid, succinic acid, malic acid and tartaric acid. The organicsalt-forming agents may themselves have pharmaceutical activity, forexample penicillins, especially penicillins G and V, as well ascarbenicillin, cephalosporins, pantothenoic acid, chloramphenicolsemisuccinate, salilylic acid, ascorbic acid and nalidixinic acid. Thesalts may be prepared, for example by mixing stoichiometric amounts ofthe components in a polar solvent, for example water, alcohol ordimethylformamide, whereupon the salt either precipitates or can beisolated by evaporation, lyophilization or precipitation.

2-Carboxamido-substituted tetracycline derivatives have successfullybeen employed for many years in the treatment of bacterial infections.In contradistinction to the compounds from which they are derived, theycan also be administered in simple manner by the parenteral route. Thisroute ensures a rapid and high concentration of the active substances inthe blood, which is important especially in critical cases.

The compounds of formula I are valuable chemotherapeutic substanceswhich have the same antibacterial activity spectrum as the startingantibiotics of formula II, they have no influence on the cardiovascularsystem, when administered parenterally, for example no suppression ofthe blood pressure nor of the cardiac frequency, and they are, however,very well absorbed when administered orally.

Another advantage of the compounds of the invention is their goodstability in the dissolved state.

The individual dosage unit in which the compounds of formula I are to beadministered depends on the nature and degree of the infection and mayvary from about 2 to 20 mg/kg, preferably from about 3 to 10 mg/kg ofbody weight.

As pharmaceutical preparations, there are mentioned, for exampletablets, dragees or capsules, which may contain, in addition to theproducts of the invention, the usual carriers and adjuvants, for exampletalc, starch, lactose or magnesium stearate. The active substances mayalso be administered as solutions, for example in water or in aqueousbuffer solutions at pH-values of from 4 to 9, these solutions having tobe prepared prior to their administration. It is also possible tocombine the products of the invention with other chemotherapeuticsubstances, for example those having antibacterial activity, such aspenicillins, chloroamphenicol, gentamycin or sulfonamides.

As examples of compounds of formula I to be prepared according to theinvention, there may especially be mentioned the derivatives of thetetracyclines mentioned in Table I, oxytetracyclines mentioned in TableII, chlorotetracyclines mentioned in Table III,6-desoxy-oxytetracyclines mentioned in Table IV and6-desmethyl-7-chloro-tetracyclines mentioned in Table V; those parts ofthe tables marked with A contain particularly preferable compounds ofthe invention.

For the purpose of a better survey, the following Tables only containthe substituents R₁ to R₇ instead of naming each individual compound.These substituents seen together with the general formula I ##SPC4##

immediately reveal the constitution of the individual compounds.

                  TABLE IA                                                        ______________________________________                                        R.sub.1                                                                             R.sub.2 R.sub.3         R.sub.4                                                                            R.sub.5                                                                            R.sub.6                                                                            R.sub.7                          ______________________________________                                        CH.sub.3                                                                            CH.sub.3                                                                              CH.sub.3        H    OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            CH.sub.3                                                                              C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             H    OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             H    OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            H       CH.sub.2 --COOH H    OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 H    OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            H       CH.sub.3 --CH--COOH                                                                           H    OH   CH.sub.3                                                                           H                                              |                                                      CH.sub.3                                                                            H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             H    OH   CH.sub.3                                                                           H                                              |                                                      CH.sub.3                                                                            H       --CH.sub.2 --CH.sub.2 --COOH                                                                  H    OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    H    OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            H       --(CH.sub.2).sub.4 --CH--COOH                                                                 H    OH   CH.sub.3                                                                           H                                              |                                                                    NH.sub.2                                                        CH.sub.3                      H    OH   CH.sub.3                                                                           H                                CH.sub.3                      H    OH   CH.sub.3                                                                           H                                CH.sub.3                      H    OH   CH.sub.3                                                                           H                                CH.sub.3                      H    OH   CH.sub.3                                                                           H                                CH.sub.3                      H    OH   CH.sub.3                                                                           H                                CH.sub.3                      H    OH   CH.sub.3                                                                           H                                CH.sub.3                      H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     CH.sub.3                                                                              CH.sub.3        H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     CH.sub.3                                                                              C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       CH.sub.2 --COOH H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       CH.sub.3 --CH--COOH                                                                           H    OH   CH.sub.3                                                                           H                                              |                                                      C.sub.2 H.sub.5                                                                     H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             H    OH   CH.sub.3                                                                           H                                              |                                                      C.sub.2 H.sub.5                                                                     H       --CH.sub.2 --CH.sub.2 --COOH                                                                  H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       --(CH.sub.2).sub.4 --CH--COOH                                                                 H    OH   CH.sub.3                                                                           H                                              |                                                                    NH.sub.2                                                        C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   CH.sub.3                                                                              CH.sub.3        H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   CH.sub.3                                                                              C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       CH.sub.2 --COOH H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       CH.sub.3 --CH--COOH                                                                           H    OH   CH.sub.3                                                                           H                                              |                                                      n-C.sub.3 H.sub.7                                                                   H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             H    OH   CH.sub.3                                                                           H                                              |                                                      n-C.sub.3 H.sub.7                                                                   H       --CH.sub.2 --CH.sub.2 --COOH                                                                  H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       --(CH.sub.2).sub.4 --CH--COOH                                                                 H    OH   CH.sub.3                                                                           H                                              |                                                                    NH.sub.2                                                        n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   CH.sub.3                                                                              CH.sub.3        H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   CH.sub.3                                                                              C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       CH.sub.2 --COOH H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       CH.sub.3 --CH--COOH                                                                           H    OH   CH.sub.3                                                                           H                                              |                                                      n-C.sub.4 H.sub.9                                                                   H       CH.sub.3 -- CH--COOC.sub.2 H.sub.5                                                            H    OH   CH.sub.3                                                                           H                                              |                                                      n-C.sub.4 H.sub.9                                                                   H       --CH.sub.2 --CH.sub.2 --COOH                                                                  H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       --(CH.sub.2).sub.4 --CH--COOH                                                                 H    OH   CH.sub.3                                                                           H                                              |                                                                    NH.sub.2                                                        n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           H                                ______________________________________                                    

                                      TABLE IB                                    __________________________________________________________________________    R.sub.1                                                                              R.sub.2    R.sub.3        R.sub.4                                                                          R.sub.5                                                                          R.sub.6                                                                           R.sub.7                            __________________________________________________________________________    CH.sub.3                                                                             H          H              H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          CH.sub.3       H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          C.sub.2 H.sub.5                                                                              H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          n-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          n-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                             H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2            H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 CON(CH.sub.3).sub.2                                                               H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --NO                                                                   H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                         H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          CH.sub.3                                                                             --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H                         H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H                         H  OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H                         H  OH CH.sub.3                                                                          H                                  CH.sub.3                         H  OH CH.sub.3                                                                          H                                  CH.sub.3                         H  OH CH.sub.3                                                                          H                                  CH.sub.3                         H  OH CH.sub.3                                                                          H                                  CH.sub.3                         H  OH CH.sub.3                                                                          H                                  CH.sub.3                         H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          H              H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          CH.sub.3       H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          C.sub.2 H.sub.5                                                                              H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          n-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          n-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                             H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2            H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                             H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --NO                                                                   H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                         H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          C.sub.2 H.sub.5                                                                      --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H                         H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H                         H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H                         H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                  H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                  H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                  H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                  H  OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                  H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          H              H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          CH.sub.3       H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.5                                                                              H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          n-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          n-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                             H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2            H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                             H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --NO                                                                   H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                         H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          n-C.sub.3 H.sub.7                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H                         H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H                         H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H                         H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                H  OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          H              H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          CH.sub.3       H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.5                                                                              H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          n-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          n-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                             H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2            H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                             H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --NO                                                                   H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                         H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          n-C.sub.4 H.sub.9                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --C.sub.6 H.sub.6                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H                         H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H                         H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H                         H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          H              H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          CH.sub.3       H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.5                                                                              H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          n-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          n-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                             H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2            H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                             H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --NO                                                                   H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                         H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          i-C.sub.3 H.sub.7                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H                         H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H                         H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H                         H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                H  OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          H              H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          CH.sub.3       H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.5                                                                              H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          n-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          n-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                             H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2            H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                             H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --NO                                                                   H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                         H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          i-C.sub.4 H.sub.9                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H                         H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H                         H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H                         H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                H  OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          H              H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          CH.sub.3       H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          C.sub.2 H.sub.5                                                                              H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                             H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CH.sub. 2 --N(C.sub.2 H.sub.5).s                      ub.2           H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                             H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --NO                                                                   H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2                                                                        H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                         H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                    H  OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          sec.-C.sub.4 H.sub.9                                                                 --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H                         H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H                         H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H                         H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9             H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9             H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9             H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9             H  OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9             H  OH CH.sub.3                                                                          H                                  __________________________________________________________________________

                  TABLE IIA                                                       ______________________________________                                        R.sub.1                                                                             R.sub.2 R.sub.3         R.sub.4                                                                            R.sub.5                                                                            R.sub.6                                                                            R.sub.7                          ______________________________________                                        CH.sub.3                                                                            CH.sub.3                                                                              CH.sub.3        OH   OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            CH.sub.3                                                                              C.sub.2 H.sub.5 OH   OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 OH   OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             OH   OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            n-C.sub.4 H.sub.9                                                                     n-C.sub. 4 H.sub.9                                                                            OH   OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            H       CH.sub.2 --COOH OH   OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 OH   OH   CH.sub.3                                                                           H                                              |                                                      CH.sub.3                                                                            H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             OH   OH   CH.sub.3                                                                           H                                              |                                                      CH.sub.3                                                                            H       --CH.sub.2 --CH.sub.2 --COOH                                                                  OH   OH   CH.sub. 3                                                                          H                                CH.sub.3                                                                            H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    OH   OH   CH.sub.3                                                                           H                                CH.sub.3                                                                            H       --(CH.sub.2).sub.4 --CH--COOH                                                                 OH   OH   CH.sub.3                                                                           H                                              |                                                                    NH.sub.2                                                        CH.sub.3                      OH   OH   CH.sub.3                                                                           H                                CH.sub.3                      OH   OH   CH.sub.3                                                                           H                                CH.sub.3                      OH   OH   CH.sub.3                                                                           H                                CH.sub.3                      OH   OH   CH.sub.3                                                                           H                                CH.sub.3                      OH   OH   CH.sub.3                                                                           H                                CH.sub.3                      OH   OH   CH.sub.3                                                                           H                                CH.sub.3                      OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     CH.sub.3                                                                              CH.sub.3        OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     CH.sub.3                                                                              C.sub.2 H.sub.5 OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       CH.sub.2 --COOH OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub. 5                                                                    H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       CH.sub.3 --CH--COOH                                                                           OH   OH   CH.sub.3                                                                           H                                              |                                                      C.sub.2 H.sub.5                                                                     H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             OH   OH   CH.sub.3                                                                           H                                              |                                                      C.sub.2 H.sub.5                                                                     H       --CH.sub.2 --CH.sub.2 --COOH                                                                  OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       --(CH.sub.2).sub.4 --CH--COOH                                                                 OH   OH   CH.sub.3                                                                           H                                              |                                                                    NH.sub.2                                                        C.sub.2 H.sub.5               OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5               OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5               OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5               OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5               OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5               OH   OH   CH.sub.3                                                                           H                                C.sub.2 H.sub.5               OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   CH.sub.3                                                                              CH.sub.3        OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   CH.sub.3                                                                              C.sub.2 H.sub.5 OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       CH.sub.2 --COOH OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       CH.sub.3 --CH--COOH                                                                           OH   OH   CH.sub.3                                                                           H                                              |                                                      n-C.sub.3 H.sub.7                                                                   H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             OH   OH   CH.sub. 3                                                                          H                                              |                                                      n-C.sub.3 H.sub.7                                                                   H       --CH.sub.2 --CH.sub.2 --COOH                                                                  OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       --(CH.sub.2).sub.4 --CH-- COOH                                                                OH   OH   CH.sub.3                                                                           H                                              |                                                                    NH.sub.2                                                        n-C.sub.3 H.sub.7             OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             OH   OH   CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   CH.sub.3                                                                              CH.sub.3        OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   CH.sub.3                                                                              C.sub.2 H.sub.5 OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       CH.sub.2 --COOH OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       CH.sub.3 --CH--COOH                                                                           OH   OH   CH.sub.3                                                                           H                                              |                                                      n-C.sub.4 H.sub.9                                                                   H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             OH   OH   CH.sub.3                                                                           H                                              |                                                      n-C.sub.4 H.sub.9                                                                   H       --CH.sub.2 --CH.sub.2 --COOH                                                                  OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       --(CH.sub.2).sub.4 --CH--COOH                                                                 OH   OH   CH.sub.3                                                                           H                                              |                                                                    NH.sub.2                                                        n-C.sub.4 H.sub.9             OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             OH   OH   CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             OH   OH   CH.sub.3                                                                           H                                ______________________________________                                    

    __________________________________________________________________________    R.sub.1                                                                              R.sub.2    R.sub.3        R.sub.4                                                                          R.sub.5                                                                          R.sub.6                                                                           R.sub.7                            __________________________________________________________________________    CH.sub.3                                                                             H          H              OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          CH.sub.3       OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          C.sub.2 H.sub.5                                                                              OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          n-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          n-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                    OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                             OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2            OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                             OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --NO                                                                   OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                         OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          CH.sub.3                                                                             --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H                         OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H                         OH OH CH.sub.3                                                                          H                                  CH.sub.3                                                                             H                         OH OH CH.sub.3                                                                          H                                  CH.sub.3                         OH OH CH.sub.3                                                                          H                                  CH.sub.3                         OH OH CH.sub.3                                                                          H                                  CH.sub.3                         OH OH CH.sub.3                                                                          H                                  CH.sub.3                         OH OH CH.sub.3                                                                          H                                  CH.sub.3                         OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          H              OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          CH.sub.3       OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          C.sub.2 H.sub.5                                                                              OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          n-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          n-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                    OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                H.sub.5).sub.2   --CH.sub.2 --CH.sub.2 --N(C.sub.-                                  OH         OH             CH.sub.3                                                                         H                                         C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2            OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                             OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --NO                                                                   OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                         OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub. 5                                                                     --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          C.sub.2 H.sub.5                                                                      --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H                         OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H                         OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                                                                      H                         OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                  OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                  OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                  OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                  OH OH CH.sub.3                                                                          H                                  C.sub.2 H.sub.5                  OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          H              OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          CH.sub.3       OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.5                                                                              OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          n-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          n-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub. 2 --CH.sub.2 --N(CH.sub.3).sub.2                                                   OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                             OH OH CH.sub. 3                                                                         H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             OH OH CH.sub. 3                                                                         H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         OH OH CH.sub. 3                                                                         H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2            OH OH CH.sub. 3                                                                         H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                             OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub. 3                                                                         H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --NO                                                                   OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                         OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub. 7                                                                   --CH.sub.2 --CH--CH.sub. 3                                                               --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          n-C.sub.3 H.sub. 7                                                                   --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub. 3                                                                         H                                  n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H                         OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H                         OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                                                                    H                         OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                OH OH CH.sub.3                                                                          H                                  n-C.sub.3 H.sub.7                OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          H              OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          CH.sub.3       OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.5                                                                              OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          n-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          n-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                    OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                             OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2            OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                             OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N0                                                                   H  OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --NN--CH.sub. 3                                                        OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub. 3                                                                         H                                  n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          n-C.sub.4 H.sub.9                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H                         OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H                         OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                                                                    H                         OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                OH OH CH.sub.3                                                                          H                                  n-C.sub.4 H.sub.9                OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          H              OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          CH.sub.3       OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.5                                                                              OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          n-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          n-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                    OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                             OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2            OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                             OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --NO                                                                   OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                         OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    C.sub. H.sub.4 OH                                                                        C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          i-C.sub.3 H.sub.7                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H                         OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H                         OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                                                                    H                         OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                OH OH CH.sub.3                                                                          H                                  i-C.sub.3 H.sub.7                OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          H              OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          CH.sub.3       OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.5                                                                              OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          n-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          n-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                    OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                             OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2            OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                             OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --NO                                                                   OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                         OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          i-C.sub.4 H.sub.9                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H                         OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H                         OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                                                                    H                         OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                OH OH CH.sub.3                                                                          H                                  i-C.sub.4 H.sub.9                OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          H              OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          CH.sub.3       OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          C.sub.2 H.sub.5                                                                              OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                                    |                                                                    OH                                                          sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                    OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                             OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                             OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                         OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2            OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                             OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                  OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                      OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --NO                                                                   OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2                                                                        OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                         OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                           OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                           OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                            OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                            OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                    OH OH CH.sub.3                                                                          H                                         | |                                                         OH         OH                                                          sec.-C.sub.4 H.sub.9                                                                 --CH.sub.3 C.sub.2 H.sub.4 OH                                                                           OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                          OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                 OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                      OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H                         OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H                         OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9                                                                 H                         OH OH CH.sub.5                                                                          H                                  sec.-C.sub.4 H.sub.9             OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9             OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9             OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9             OH OH CH.sub.3                                                                          H                                  sec.-C.sub.4 H.sub.9             OH OH CH.sub.3                                                                          H                                  __________________________________________________________________________

                  TABLE IIIA                                                      ______________________________________                                        R.sub.1                                                                             R.sub.2 R.sub.3         R.sub.4                                                                            R.sub.5                                                                            R.sub.6                                                                            R.sub.7                          ______________________________________                                        CH.sub.3                                                                            CH.sub.3                                                                              CH.sub.3        H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                                                                            CH.sub.3                                                                              C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                                                                            C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                                                                            n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                                                                            n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                                                                            H       CH.sub.2 --COOH H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                                                                            H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                                                                            H       CH.sub.3 --CH--COOH                                                                           H    OH   CH.sub.3                                                                           Cl                                             |                                                      CH.sub.3                                                                            H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             H    OH   CH.sub.3                                                                           Cl                                             |                                                      CH.sub.3                                                                            H       --CH.sub.2 --CH.sub.2 --COOH                                                                  H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                                                                            H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                                                                            H       --(CH.sub.2).sub.4 --CH--COOH                                                                 H    OH   CH.sub.3                                                                           Cl                                             |                                                                    NH.sub.2                                                        CH.sub.3                      H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                      H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                      H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                      H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                      H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                      H    OH   CH.sub.3                                                                           Cl                               CH.sub.3                      H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5                                                                     CH.sub.3                                                                              CH.sub.3        H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5                                                                     CH.sub.3                                                                              C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5                                                                     C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5                                                                     n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5                                                                     n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5                                                                     H       CH.sub.2 --COOH H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5                                                                     H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5                                                                     H       CH.sub.3 --CH--COOH                                                                           H    OH   CH.sub.3                                                                           Cl                                             |                                                      C.sub.2 H.sub.5                                                                     H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             H    OH   CH.sub.3                                                                           Cl                                             |                                                      C.sub.2 H.sub.5                                                                     H       --CH.sub.2 --CH.sub.2 --COOH                                                                  H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5                                                                     H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5                                                                     H       --(CH.sub.2).sub.4 --CH--COOH                                                                 H    OH   CH.sub.3                                                                           Cl                                             |                                                                    NH.sub.2                                                        C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           Cl                               C.sub.2 H.sub.5               H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7                                                                   CH.sub.3                                                                              CH.sub.3        H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7                                                                   CH.sub.3                                                                              C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7                                                                   C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7                                                                   n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7                                                                   n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7                                                                   H       CH.sub.2 --COOH H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7                                                                   H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7                                                                   H       CH.sub.3 --CH--COOH                                                                           H    OH   CH.sub.3                                                                           Cl                                             |                                                      n-C.sub.3 H.sub.7                                                                   H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             H    OH   CH.sub.3                                                                           Cl                                             |                                                      n-C.sub.3 H.sub.7                                                                   H       --CH.sub.2 --CH.sub.2 --COOH                                                                  H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7                                                                   H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7                                                                   H       --(CH.sub.2).sub.4 --CH--COOH                                                                 H    OH   CH.sub.3                                                                           Cl                                             |                                                                    NH.sub.2                                                        n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.3 H.sub.7             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9                                                                   CH.sub.3                                                                              CH.sub.3        H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9                                                                   CH.sub.3                                                                              C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9                                                                   C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9                                                                   n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9                                                                   n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9                                                                   H       CH.sub.2 --COOH H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9                                                                   H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9                                                                   H       CH.sub.3 --CH--COOH                                                                           H    OH   CH.sub.3                                                                           Cl                                             |                                                      n-C.sub.4 H.sub.9                                                                   H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             H    OH   CH.sub.3                                                                           Cl                                             |                                                      n-C.sub.4 H.sub.9                                                                   H       --CH.sub.2 --CH.sub.2 --COOH                                                                  H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9                                                                   H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9                                                                   H       --(CH.sub.2).sub.4 --CH--COOH                                                                 H    OH   CH.sub.3                                                                           Cl                                             |                                                                    NH.sub.2                                                        n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           Cl                               n-C.sub.4 H.sub.9             H    OH   CH.sub.3                                                                           Cl                               ______________________________________                                    

                                      TABLE IIIB                                  __________________________________________________________________________    R.sub.1                                                                              R.sub.2    R.sub.3          R.sub.4                                                                          R.sub.5                                                                          R.sub.6                                                                           R.sub.7                          __________________________________________________________________________    CH.sub.3                                                                             H          H                H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          CH.sub.3         H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          C.sub.2 H.sub.5  H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          n-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          n-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                                                          Cl                                                 |                                                                    OH                                                          CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2              H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H                           H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --NO                                                                     H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H                           H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                           H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                                                          Cl                                      | |                                                         OH         OH                                                          CH.sub.3                                                                             --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H                           H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H                           H  OH CH.sub.3                                                                          Cl                               CH.sub.3                                                                             H                           H  OH CH.sub.3                                                                          Cl                               CH.sub.3                           H  OH CH.sub.3                                                                          Cl                               CH.sub.3                           H  OH CH.sub.3                                                                          Cl                               CH.sub.3                           H  OH CH.sub.3                                                                          Cl                               CH.sub.3                           H  OH CH.sub.3                                                                          Cl                               CH.sub.3                           H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          H                H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          CH.sub.3         H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          C.sub.2 H.sub.5  H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          n-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          n-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                                                          Cl                                                 |                                                                    OH                                                          C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2              H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H                           H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --NO                                                                     H  OH CH.sub.3                             C.sub.2 H.sub.5                                                                      H                           H  OH CH.sub.3                             C.sub.2 H.sub.5                                                                      H          --CH.sub. 2 --CH.sub.2 --NN--CH.sub.3                                                          H  OH CH.sub.3                             C.sub.2 H.sub.5                                                                      n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                             C.sub.2 H.sub.5                                                                      n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                             C.sub.2 H.sub.5                                                                      i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                             C.sub.2 H.sub.5                                                                      i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                             C.sub.2 H.sub.5                                                                      C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                             C.sub.2 H.sub.5                                                                      --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                    | |                                                         OH         OH                                                          C.sub.2 H.sub.5                                                                      --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                             C.sub.2 H.sub.5                                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub. 2 OH                                                           H  OH CH.sub.3                             C.sub.2 H.sub.5                                                                      --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H                           H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H                           H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                                                                      H                           H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                    H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                    H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                    H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                    H  OH CH.sub.3                                                                          Cl                               C.sub.2 H.sub.5                    H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          H                H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          CH.sub.3         H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.5  H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          n-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          n-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                                                          Cl                                                 |                                                                    OH                                                          n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2              H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H                           H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N O                                                                    H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H                           H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N N--CH.sub.3                                                          H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                                                          Cl                                      | |                                                         OH         OH                                                          n-C.sub.3 H.sub.7                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H                           H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H                           H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                                                                    H                           H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                  H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                  H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                  H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                  H  OH CH.sub.3                                                                          Cl                               n-C.sub.3 H.sub.7                  H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          H                H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          CH.sub.3         H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.5  H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          n-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          n-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                                                          Cl                                                 |                                                                    OH                                                          n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2              H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H                           H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N O                                                                    H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H                           H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N N--CH.sub.3                                                          H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                                                          Cl                                      | |                                                         OH         OH                                                          n-C.sub.4 H.sub.9                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H                           H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H                           H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                                                                    H                           H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                  H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                  H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                  H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                  H  OH CH.sub.3                                                                          Cl                               n-C.sub.4 H.sub.9                  H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          H                H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          CH.sub.3         H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.5  H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          n-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          n-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                                                          Cl                                                 |                                                                    OH                                                          i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2              H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H                           H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --NO                                                                     H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H                           H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N N--CH.sub.3                                                          H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                                                          Cl                                      | |                                                         OH         OH                                                          i-C.sub.3 H.sub.7                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H                           H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H                           H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                                                                    H                           H  OH CH.sub. 3                                                                         Cl                               i-C.sub.3 H.sub.7                  H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                  H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                  H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                  H  OH CH.sub.3                                                                          Cl                               i-C.sub.3 H.sub.7                  H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          H                H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          CH.sub.3         H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.5  H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          n-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          n-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                                                          Cl                                                 |                                                                    OH                                                          i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2              H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H                           H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --NO                                                                     H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H                           H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N N--CH.sub.3                                                          H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                                                          Cl                                      | |                                                         OH         OH                                                          i-C.sub.4 H.sub.9                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H                           H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H                           H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                                                                    H                           H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                  H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                  H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                  H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                  H  OH CH.sub.3                                                                          Cl                               i-C.sub.4 H.sub.9                  H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          H                H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          CH.sub.3         H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          C.sub.2 H.sub.5  H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                                                          Cl                                                 |                                                                    OH                                                          sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2              H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H                           H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --NO                                                                     H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H                           H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N N--CH.sub.3                                                          H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                      H  OH CH.sub.3                                                                          Cl                                      | |                                                         OH         OH                                                          sec.-C.sub.4 H.sub.9                                                                 --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H                           H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H                           H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9                                                                 H                           H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9               H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9               H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9               H  OH CH.sub.3                                                                          Cl                               sec.-C.sub.4 H.sub.9               H  OH CH.sub. 3                                                                         Cl                               sec.-C.sub.4 H.sub.9               H  OH CH.sub.3                                                                          Cl                               __________________________________________________________________________

                  TABLE IVA                                                       ______________________________________                                        R.sub.1                                                                             R.sub.2 R.sub.3         R.sub.4                                                                            R.sub.5                                                                            R.sub.6                                                                            R.sub.7                          ______________________________________                                        CH.sub.3                                                                            CH.sub.3                                                                              CH.sub.3        OH   H    CH.sub.3                                                                           H                                CH.sub.3                                                                            CH.sub.3                                                                              C.sub.2 H.sub.5 OH   H    CH.sub.3                                                                           H                                CH.sub.3                                                                            C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 OH   H    CH.sub.3                                                                           H                                CH.sub.3                                                                            n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             OH   H    CH.sub.3                                                                           H                                CH.sub.3                                                                            n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             OH   H    CH.sub.3                                                                           H                                CH.sub.3                                                                            H       CH.sub.2 --COOH OH   H    CH.sub.3                                                                           H                                CH.sub.3                                                                            H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 OH   H    CH.sub.3                                                                           H                                CH.sub.3                                                                            H       CH.sub.3 --CH--COOH                                                                           OH   H    CH.sub.3                                                                           H                                              |                                                      CH.sub.3                                                                            H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             OH   H    CH.sub.3                                                                           H                                              |                                                      CH.sub.3                                                                            H       --CH.sub.2 --CH.sub.2 --COOH                                                                  OH   H    CH.sub.3                                                                           H                                CH.sub.3                                                                            H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    OH   H    CH.sub.3                                                                           H                                CH.sub.3                                                                            H       --(CH.sub.2).sub.4 --CH--COOH                                                                 OH   H    CH.sub.3                                                                           H                                              |                                                                    NH.sub.2                                                        CH.sub.3                      OH   H    CH.sub.3                                                                           H                                CH.sub.3                      OH   H    CH.sub.3                                                                           H                                CH.sub.3                      OH   H    CH.sub.3                                                                           H                                CH.sub.3                      OH   H    CH.sub.3                                                                           H                                CH.sub.3                      OH   H    CH.sub.3                                                                           H                                CH.sub.3                      OH   H    CH.sub.3                                                                           H                                CH.sub.3                      OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     CH.sub.3                                                                              CH.sub.3        OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     CH.sub.3                                                                              C.sub.2 H.sub.5 OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       CH.sub.2 -COOH  OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       CH.sub.3 --CH--COOH                                                                           OH   H    CH.sub.3                                                                           H                                              |                                                      C.sub.2 H.sub.5                                                                     H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             OH   H    CH.sub.3                                                                           H                                              |                                                      C.sub.2 H.sub.5                                                                     H       --CH.sub.2 --CH.sub.2 --COOH                                                                  OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5                                                                     H       --(CH.sub.2).sub.4 --CH--COOH                                                                 OH   H    CH.sub.3                                                                           H                                              |                                                                    NH.sub.2                                                        C.sub.2 H.sub.5               OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5               OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub. 5              OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5               OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5               OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5               OH   H    CH.sub.3                                                                           H                                C.sub.2 H.sub.5               OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   CH.sub.3                                                                              CH.sub.3        OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   CH.sub.3                                                                              C.sub.2 H.sub.5 OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       CH.sub.2 --COOH OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       CH.sub.3 --CH--COOH                                                                           OH   H    CH.sub.3                                                                           H                                              |-n-C.sub.3 H.sub.7                                                                  H    CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                  OH   H CH.sub.3 H                                   |                                                      n-C.sub.3 H.sub.7                                                                   H       --CH.sub.2 --CH.sub.2 --COOH                                                                  OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7                                                                   H       --(CH.sub.2).sub.4 --CH--COOH                                                                 OH   H    CH.sub.3                                                                           H                                              |-          NH.sub.2                                   n-C.sub.3 H.sub.7             OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             OH   H    CH.sub.3                                                                           H                                n-C.sub.3 H.sub.7             OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   CH.sub.3                                                                              CH.sub.3        OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   CH.sub.3                                                                              C.sub.2 H.sub.5 OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   C.sub.2 H.sub.5                                                                       C.sub.2 H.sub.5 OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   n-C.sub.3 H.sub.7                                                                     n-C.sub.3 H.sub.7                                                                             OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   n-C.sub.4 H.sub.9                                                                     n-C.sub.4 H.sub.9                                                                             OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       CH.sub.2 --COOH OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       CH.sub.2 --COOC.sub.2 H.sub.5                                                                 OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       CH.sub.3 --CH--COOH                                                                           OH   H    CH.sub.3                                                                           H                                              |                                                      n-C.sub.4 H.sub.9                                                                   H       CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                             OH   H    CH.sub.3                                                                           H                                              |                                                      n-C.sub.4 H.sub.9                                                                   H       --CH.sub.2 --CH.sub.2 --COOH                                                                  OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                    OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9                                                                   H       --(CH.sub.2).sub.4 --CH--COOH                                                                 OH   H    CH.sub.3                                                                           H                                              |-          NH.sub.2                                   n-C.sub.4 H.sub.9             OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             OH   H    CH.sub. 3                                                                          H                                n-C.sub.4 H.sub.9             OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             OH   H    CH.sub.3                                                                           H                                n-C.sub.4 H.sub.9             OH   H    CH.sub.3                                                                           H                                ______________________________________                                    

                                      TABLE IVB                                   __________________________________________________________________________    R.sub.1                                                                              R.sub.2    R.sub.3          R.sub.4                                                                          R.sub.5                                                                          R.sub.6                                                                           R.sub.7                          __________________________________________________________________________    CH.sub.3                                                                             H          H                OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          CH.sub.3         OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          C.sub.2 H.sub.5  OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          n-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          n-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                                  OH                                                          CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2              OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H                           OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N                                                                      OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H                           OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H          --CH.sub.2 --CH.sub.2 --N N--CH.sub.3                                                          OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                       | |                                                         OH         OH                                                          CH.sub.3                                                                             --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H                           OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H                           OH H  CH.sub.3                                                                          H                                CH.sub.3                                                                             H                           OH H  CH.sub.3                                                                          H                                CH.sub.3                           OH H  CH.sub.3                                                                          H                                CH.sub.3                           OH H  CH.sub.3                                                                          H                                CH.sub.3                           OH H  CH.sub.3                                                                          H                                CH.sub.3                           OH H  CH.sub.3                                                                          H                                CH.sub.3                           OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          H                OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          CH.sub.3         OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          C.sub.2 H.sub.5  OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          n-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          n-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                                  |                                                                    OH                                                          C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2              OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H                           OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --N O                                                                    OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H                           OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H          --CH.sub.2 --CH.sub.2 --N N--CH.sub.3                                                          OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      C.sub.2 H.sub.4 OH                                                                       Ck.sub.2 H.sub.4 OH                                                                            OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      --CH--CH--CH.sub. 3                                                                      --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                       | |                                                         OH         OH                                                          C.sub.2 H.sub.5                                                                      --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H                           OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H                           OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                                                                      H                           OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                    OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                    OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                    OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                    OH H  CH.sub.3                                                                          H                                C.sub.2 H.sub.5                    OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          H                OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          CH.sub.3         OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.5  OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          n-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          n-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                                  |                                                                    OH                                                          n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2              OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H                           OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N O                                                                    OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H                           OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N N--CH.sub.3                                                          OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                       | |                                                         OH         OH                                                          n-C.sub.3 H.sub.7                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H                           OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H                           OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                                                                    H                           OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                  OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                  OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                  OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                  OH H  CH.sub.3                                                                          H                                n-C.sub.3 H.sub.7                  OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          H                OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          CH.sub.3         OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.5  OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          n-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          n-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                                  |                                                                    OH                                                          n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2              OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H                           OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N O                                                                    OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H                           OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N N--CH.sub.3                                                          OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                       | |                                                         OH         OH                                                          n-C.sub.4 H.sub.9                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H                           OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                                                                    H                           OH H  CH.sub.3                                                                          H                                n-CH.sub.4 H.sub.9                                                                   H                           OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                  OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                  OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                  OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                  OH H  CH.sub.3                                                                          H                                n-C.sub.4 H.sub.9                  OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          H                OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          CH.sub.3         OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.5  OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          n-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          n-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                                  |                                                                    OH                                                          i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2              OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H                           OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --NO                                                                     OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H                           OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                           OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                       | |                                                         OH         OH                                                          i-C.sub.3 H.sub.7                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 CH.sub.2 CH.sub.2 OH                                                                OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H                           OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H                           OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                                                                    H                           OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                  OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                  OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                  OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                  OH H  CH.sub.3                                                                          H                                i-C.sub.3 H.sub.7                  OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          H                OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          CH.sub.3         OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.5  OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          n-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          n-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                                  |                                                                    OH                                                          i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).su                      b.2              OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H                           OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --NO                                                                     OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H                           OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                           OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                       | |                                                         OH         OH                                                          i-C.sub.4 H.sub.9                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H                           OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H                           OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                                                                    H                           OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                  OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                  OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                  OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                  OH H  CH.sub.3                                                                          H                                i-C.sub.4 H.sub.9                  OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          H                OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          CH.sub.3         OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          C.sub.2 H.sub.5  OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                                  |                                                                    OH                                                          sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                      OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                               OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                               OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                           OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CH.sub.2 N(C.sub.2 H.sub.5).sub.                      2                OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                               OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                    OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                        OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H                           OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --NO                                                                     OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H                           OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H          --CH.sub.2 --CH.sub.2 --N N--CH.sub.3                                                          OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11                                                                             OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13                                                                             OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7                                                                              OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9                                                                              OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                      OH H  CH.sub.3                                                                          H                                       | |                                                         OH         OH                                                          sec.-C.sub.4 H.sub.9                                                                 --CH.sub.3 C.sub.2 H.sub.4 OH                                                                             OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                            OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                   OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                        OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H                           OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H                           OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9                                                                 H                           OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9               OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9               OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9               OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9               OH H  CH.sub.3                                                                          H                                sec.-C.sub.4 H.sub.9               OH H  CH.sub.3                                                                          H                                __________________________________________________________________________

                                      TABLE VA                                    __________________________________________________________________________    R.sub.1                                                                           R.sub.2        R.sub.3      R.sub.4                                                                         R.sub.5                                                                          R.sub.6                                                                         R.sub.7                                __________________________________________________________________________    CH.sub.3                                                                          CH.sub.3       CH.sub.3     H OH H Cl                                     CH.sub.3                                                                          CH.sub.3       C.sub.2 H.sub.5                                                                            H OH H Cl                                     CH.sub.3                                                                          C.sub.2 H.sub.5                                                                              C.sub.2 H.sub.5                                                                            H OH H Cl                                     CH.sub.3                                                                          n-C.sub.3 H.sub.7                                                                            n-C.sub.3 H.sub.7                                                                          H OH H Cl                                     CH.sub.3                                                                          n-C.sub.4 H.sub.9                                                                            n-C.sub.4 H.sub.9                                                                          H OH H Cl                                     CH.sub.3                                                                          H              CH.sub.2 --COOH                                                                            H OH H Cl                                     CH.sub.3                                                                          H              CH.sub.2 --COOC.sub.2 H.sub.5                                                              H OH H Cl                                     CH.sub.3                                                                          H              CH.sub.3 --CH--COOH                                                                        H OH H Cl                                                        |                                                 CH.sub.3                                                                          H              CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                          H OH H Cl                                                        |                                                 CH.sub.3                                                                          H              --CH.sub.2 --CH.sub.2 --COOH                                                               H OH H Cl                                     CH.sub.3                                                                          H              --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                 H OH H Cl                                     CH.sub.3                                                                          H              --(CH.sub.2).sub.4 --CH--COOH                                                              H OH H Cl                                                        |                                                                    NH.sub.2                                                   CH.sub.3                        H OH H Cl                                     CH.sub.3                        H OH H Cl                                     CH.sub.3                        H OH H Cl                                     CH.sub.3                        H OH H Cl                                     CH.sub.3                        H OH H Cl                                     CH.sub.3                        H OH H Cl                                     CH.sub.3                        H OH H Cl                                     C.sub.2 H.sub.5                                                                   CH.sub.3       CH.sub.3     H OH H Cl                                     C.sub.2 H.sub.5                                                                   CH.sub.3       C.sub.2 H.sub.5                                                                            H OH H Cl                                     C.sub.2 H.sub.5                                                                   C.sub.2 H.sub.5                                                                              C.sub.2 H.sub.5                                                                            H OH H Cl                                     C.sub.2 H.sub.5                                                                   n-C.sub.3 H.sub.7                                                                            n-C.sub.3 H.sub.7                                                                          H OH H Cl                                     C.sub.2 H.sub.5                                                                   n-C.sub.4 H.sub.9                                                                            n-C.sub.4 H.sub.9                                                                          H OH H Cl                                     C.sub.2 H.sub.5                                                                   H              CH.sub.2 --COOH                                                                            H OH H Cl                                     C.sub.2 H.sub.5                                                                   H              CH.sub.2 --COOC.sub.2 H.sub.5                                                              H OH H Cl                                     C.sub.2 H.sub.5                                                                   H              CH.sub.3 --CH--COOH                                                                        H OH H Cl                                                        |                                                 C.sub.2 H.sub.5                                                                   H              CH.sub.3 --CH--COOC.sub. 2 H.sub.5                                                         H OH H Cl                                                        |                                                 C.sub.2 H.sub.5                                                                   H              --CH.sub.2 --CH.sub.2 --COOH                                                               H OH H Cl                                     C.sub.2 H.sub.5                                                                   H              --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                 H OH H Cl                                     C.sub.2 H.sub.5                                                                   H              --(CH.sub.2).sub.4 --CH--COOH                                                              H OH H Cl                                                        |                                                                    NH.sub.2                                                   C.sub.2 H.sub.5                 H OH H Cl                                     C.sub.2 H.sub.5                 H OH H Cl                                     C.sub.2 H.sub.5                 H OH H Cl                                     C.sub.2 H.sub.5                 H OH H Cl                                     C.sub.2 H.sub.5                 H OH H Cl                                     C.sub.2 H.sub.5                 H OH H Cl                                     C.sub.2 H.sub.5                 H OH H Cl                                     n-C.sub.3 H.sub.7                                                                 CH.sub.3       CH.sub.3     H OH H Cl                                     n-C.sub.3 H.sub.7                                                                 CH.sub.3       C.sub.2 H.sub.5                                                                            H OH H Cl                                     n-C.sub.3 H.sub.7                                                                 C.sub.2 H.sub.5                                                                              C.sub.2 H.sub.5                                                                            H OH H Cl                                     n-C.sub.3 H.sub.7                                                                 n-C.sub.3 H.sub.7                                                                            n-C.sub.3 H.sub.7                                                                          H OH H Cl                                     n-C.sub.3 H.sub.7                                                                 n-C.sub.4 H.sub.9                                                                            n-C.sub.4 H.sub.9                                                                          H OH H Cl                                     n-C.sub.3 H.sub.7                                                                 H              CH.sub.2 --COOH                                                                            H OH H Cl                                     n-C.sub.3 H.sub.7                                                                 H              CH.sub.2 --COOC.sub.2 H.sub.5                                                              H OH H Cl                                     n-C.sub.3 H.sub.7                                                                 H              CH.sub.3 --CH--COOH                                                                        H OH H Cl                                                        |                                                 n-C.sub.3 H.sub.7                                                                 H              CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                          H OH H Cl                                                        |                                                 n-C.sub.3 H.sub.7                                                                 H              --CH.sub.2 --CH.sub.2 --COOH                                                               H OH H Cl                                     n-C.sub.3 H.sub.7                                                                 H              --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                 H OH H Cl                                     n-C.sub.3 H.sub.7                                                                 H              --(CH.sub.2).sub.4 --CH--COOH                                                              H OH H Cl                                                        |                                                                    NH.sub.2                                                   n-C.sub.3 H.sub.7               H OH H Cl                                     n-C.sub.3 H.sub.7               H OH H Cl                                     n-C.sub.3 H.sub.7               H OH H Cl                                     n-C.sub.3 H.sub.7               H OH H Cl                                     n-C.sub.3 H.sub.7               H OH H Cl                                     n-C.sub.3 H.sub.7               H OH H Cl                                     n-C.sub.3 H.sub.7               H OH H Cl                                     n-C.sub.4 H.sub.9                                                                 CH.sub.3       CH.sub.3     H OH H Cl                                     n-C.sub.4 H.sub.9                                                                 CH.sub.3       C.sub.2 H.sub.5                                                                            H OH H Cl                                     n-C.sub.4 H.sub.9                                                                 C.sub.2 H.sub.5                                                                              C.sub.2 H.sub.5                                                                            H OH H Cl                                     n-C.sub.4 H.sub.9                                                                 n-C.sub.3 H.sub.7                                                                            n-C.sub.3 H.sub.7                                                                          H OH H Cl                                     n-C.sub.4 H.sub.9                                                                 n-C.sub.4 H.sub.9                                                                            n-C.sub.4 H.sub.9                                                                          H OH H Cl                                     n-C.sub.4 H.sub.9                                                                 H              CH.sub.2 --COOH                                                                            H OH H Cl                                     n-C.sub.4 H.sub.9                                                                 H              CH.sub.2 --COOC.sub.2 H.sub.5                                                              H OH H Cl                                     n-C.sub.4 H.sub.9                                                                 H              CH.sub.3 --CH--COOH                                                                        H OH H Cl                                                        |                                                 n-C.sub.4 H.sub.9                                                                 H              CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                          H OH H Cl                                                        |                                                 n-C.sub.4 H.sub.9                                                                 H              --CH.sub.2 --CH.sub.2 --COOH                                                               H OH H Cl                                     n-C.sub.4 H.sub.9                                                                 H              --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                 H OH H Cl                                     n-C.sub.4 H.sub.9                                                                 H              --(CH.sub.2).sub.4 --CH--COOH                                                              H OH H Cl                                                        |                                                                    NH.sub.2                                                   n-C.sub.4 H.sub.9               H OH H Cl                                     n-C.sub.4 H.sub.9               H OH H Cl                                     n-C.sub.4 H.sub.9               H OH H Cl                                     n-C.sub.4 H.sub.9               H OH H Cl                                     n-C.sub.4 H.sub.9               H OH H Cl                                     n-C.sub.4 H.sub.9               H OH H Cl                                     n-C.sub.4 H.sub.9               H OH H Cl                                     __________________________________________________________________________

                                      TABLE VB                                    __________________________________________________________________________    R.sub.1                                                                            R.sub.2    R.sub.3             R.sub.4                                                                         R.sub.5                                                                          R.sub.6                                                                         R.sub.7                            __________________________________________________________________________    CH.sub.3                                                                           H          H                   H OH H Cl                                 CH.sub.3                                                                           H          CH.sub.3            H OH H Cl                                 CH.sub.3                                                                           H          C.sub.2 H.sub.5     H OH H Cl                                 CH.sub.3                                                                           H          n-C.sub.3 H.sub.7   H OH H Cl                                 CH.sub.3                                                                           H          n-C.sub.4 H.sub.9   H OH H Cl                                 CH.sub.3                                                                           H          i-C.sub.3 H.sub.7   H OH H Cl                                 CH.sub.3                                                                           H          i-C.sub.4 H.sub.9   H OH H Cl                                 CH.sub.3                                                                           H          n-C.sub.5 H.sub.11  H OH H Cl                                 CH.sub.3                                                                           H          n-C.sub.6 H.sub.13  H OH H Cl                                 CH.sub.3                                                                           H          C.sub.2 H.sub.4 OH  H OH H Cl                                 CH.sub.3                                                                           H          --CH.sub.2 --CH--CH.sub.3                                                                         H OH H Cl                                                 |                                                                    OH                                                            CH.sub.3                                                                           H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                               H OH H Cl                                 CH.sub.3                                                                           H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                         H OH H Cl                                 CH.sub.3                                                                           H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                                  H OH H Cl                                 CH.sub.3                                                                           H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                                  H OH H Cl                                 CH.sub.3                                                                           H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                              H OH H Cl                                 CH.sub.3                                                                           H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.                    2                   H OH H Cl                                 CH.sub.3                                                                           H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                                  H OH H Cl                                 CH.sub.3                                                                           H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                       H OH H Cl                                 CH.sub.3                                                                           H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                           H OH H Cl                                 CH.sub.3                                                                           H          --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 CH.sub.3                                                                           H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 CH.sub. 3                                                                          H                              H OH H Cl                                 CH.sub.3                                                                           H          --CH.sub.2 --CH.sub.2 --N O                                                                       H OH H Cl                                 CH.sub.3                                                                           H                              H OH H Cl                                 CH.sub.3                                                                           H          --CH.sub.2 --CH.sub.2 --N N--CH.sub.3                                                             H OH H Cl                                 CH.sub.3                                                                           n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11  H OH H Cl                                 CH.sub.3                                                                           n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13  H OH H Cl                                 CH.sub.3                                                                           i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7   H OH H Cl                                 CH.sub.3                                                                           i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9   H OH H Cl                                 CH.sub.3                                                                           C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH  H OH H Cl                                 CH.sub.3                                                                           --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                         H OH H Cl                                      | |                                                         OH         OH                                                            CH.sub.3                                                                           --CH.sub.3 C.sub.2 H.sub.4 OH  H OH H Cl                                 CH.sub.3                                                                           --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                               H OH H Cl                                 CH.sub.3                                                                           --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 CH.sub.3                                                                           --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 CH.sub.3                                                                           H                              H OH H Cl                                 CH.sub.3                                                                           H                              H OH H Cl                                 CH.sub.3                                                                           H                              H OH H Cl                                 CH.sub.3                            H OH H Cl                                 CH.sub.3                            H OH H Cl                                 CH.sub.3                            H OH H Cl                                 CH.sub.3                            H OH H Cl                                 CH.sub.3                            H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          H                   H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          CH.sub.3            H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          C.sub.2 H.sub.5     H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          n-C.sub.3 H.sub.7   H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          n-C.sub.4 H.sub.9   H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          i-C.sub.3 H.sub.7   H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          i-C.sub.4 H.sub.9   H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          n-C.sub.5 H.sub.11  H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          n-C.sub.6 H.sub.13  H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          C.sub.2 H.sub.4 OH  H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --CH--CH.sub.3                                                                         H OH H Cl                                                 |                                                                    OH                                                            C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                               H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                         H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                                  H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                                  H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                              H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.                    2                   H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                                  H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                       H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                           H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 C.sub.2 H.sub.5                                                                    H                              H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --CH.sub.2 --N O                                                                       H OH H Cl                                 C.sub.2 H.sub.5                                                                    H                              H OH H Cl                                 C.sub.2 H.sub.5                                                                    H          --CH.sub.2 --CH.sub.2 --N N-CH.sub.3                                                              H OH H Cl                                 C.sub.2 H.sub.5                                                                    n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11  H OH H Cl                                 C.sub.2 H.sub.5                                                                    n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13  H OH H Cl                                 C.sub.2 H.sub.5                                                                    i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7   H OH H Cl                                 C.sub.2 H.sub.5                                                                    i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9   H OH H Cl                                 C.sub.2 H.sub.5                                                                    C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH  H OH H Cl                                 C.sub.2 H.sub.5                                                                    --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH H OH H Cl                                      | |                                                         OH         OH                                                            C.sub.2 H.sub.5                                                                    --CH.sub.3 C.sub.2 H.sub.4 OH  H OH H Cl                                 C.sub.2 H.sub.5                                                                    --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                               H OH H Cl                                 C.sub.2 H.sub.5                                                                    --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 C.sub.2 H.sub.5                                                                    --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 C.sub.2 H.sub.5                                                                    H                              H OH H Cl                                 C.sub.2 H.sub.5                                                                    H                              H OH H Cl                                 C.sub.2 H.sub.5                                                                    H                              H OH H Cl                                 C.sub.2 H.sub.5                     H OH H Cl                                 C.sub.2 H.sub.5                     H OH H Cl                                 C.sub.2 H.sub.5                     H OH H Cl                                 C.sub.2 H.sub.5                     H OH H Cl                                 C.sub.2 H.sub.5                     H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          H                   H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          CH.sub.3            H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          C.sub.2 H.sub.5     H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          n-C.sub.3 H.sub.7   H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          n-C.sub.4 H.sub.9   H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          i-C.sub.3 H.sub.7   H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          i-C.sub.4 H.sub.9   H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          n-C.sub.5 H.sub.11  H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          n-C.sub.6 H.sub.13  H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          C.sub.2 H.sub.4 OH  H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH--CH.sub.3                                                                         H OH H Cl                                                 |                                                                    OH                                                            n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 CH.sub.2 --CH.sub.2 OH                                                                 H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 CH.sub.2 --N(CH.sub.3).sub.2                                                           H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                                  H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                                  H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                              H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.                    2                   H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                                  H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                       H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                           H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H                              H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --NO                                                                        H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H                              H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                              H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11  H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13  H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7   H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9   H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH  H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                         H OH H Cl                                      | |                                                         OH         OH                                                            n-C.sub.3 H.sub.7                                                                  --CH.sub.3 C.sub.2 H.sub.4 OH  H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                               H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H                              H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H                              H OH H Cl                                 n-C.sub.3 H.sub.7                                                                  H                              H OH H Cl                                 n-C.sub.3 H.sub.7                   H OH H Cl                                 n-C.sub.3 H.sub.7                   H OH H Cl                                 n-C.sub.3 H.sub.7                   H OH H Cl                                 n-C.sub.3 H.sub.7                   H OH H Cl                                 n-C.sub.3 H.sub.7                   H OH H Cl                                 n-C.sub.3 H.sub.7                   H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          H                   H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          CH.sub.3            H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          C.sub.2 H.sub.5     H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          n-C.sub.3 H.sub.7   H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          n-C.sub.4 H.sub.9   H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          i-C.sub.3 H.sub.7   H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          i-C.sub.4 H.sub.9   H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          n-C.sub.5 H.sub.11  H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          n-C.sub.6 H.sub.13  H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          C.sub.2 H.sub.4 OH  H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH--CH.sub.3                                                                         H OH H Cl                                                 |                                                                    OH                                                            n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                               H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                         H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                                  H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                                  H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.2).sub.2                                              H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.                    2                   H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                                  H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                       H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                           H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H                              H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --N                                                                         H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H                              H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                              H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11  H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13  H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7   H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9   H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH  H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                         H OH H Cl                                      | |                                                         OH         OH                                                            n-C.sub.4 H.sub.9                                                                  --CH.sub.3 C.sub.2 H.sub.4 OH  H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                               H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H                              H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H                              H OH H Cl                                 n-C.sub.4 H.sub.9                                                                  H                              H OH H Cl                                 n-C.sub.4 H.sub.9                   H OH H Cl                                 n-C.sub.4 H.sub.9                   H OH H Cl                                 n-C.sub.4 H.sub.9                   H OH H Cl                                 n-C.sub.4 H.sub.9                   H OH H Cl                                 n-C.sub.4 H.sub.9                   H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          H                   H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          CH.sub.3            H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          C.sub.2 H.sub.5     H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          n-C.sub.3 H.sub.7   H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          n-C.sub.4 H.sub.9   H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          i-C.sub.3 H.sub.7   H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          i-C.sub.4 H.sub.9   H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          n-C.sub.5 H.sub.11  H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          n-C.sub.6 H.sub.13  H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          C.sub.2 H.sub.4 OH  H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH--CH.sub.3                                                                         H OH H Cl                                                 |                                                                    OH                                                            i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                               H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                         H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                                  H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                                  H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                              H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.                    2                   H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                                  H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                       H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                           H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H                              H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --NO                                                                        H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H                              H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                              H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11  H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13  H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7   H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9   H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH  H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                         H OH H Cl                                      | |                                                         OH         OH                                                            i-C.sub.3 H.sub.7                                                                  --CH.sub.3 C.sub.2 H.sub.4 OH  H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                               H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H                              H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H                              H OH H Cl                                 i-C.sub.3 H.sub.7                                                                  H                              H OH H Cl                                 i-C.sub.3 H.sub.7                   H OH H Cl                                 i-C.sub.3 H.sub.7                   H OH H Cl                                 i-C.sub.3 H.sub.7                   H OH H Cl                                 i-C.sub.3 H.sub.7                   H OH H Cl                                 i-C.sub.3 H.sub.7                   H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          H                   H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          CH.sub.3            H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          C.sub.2 H.sub.5     H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          n-C.sub.3 H.sub.7   H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          n-C.sub.4 H.sub.9   H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          i-C.sub.3 H.sub.7   H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          i-C.sub.4 H.sub.9   H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          n-C.sub.5 H.sub.11  H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          n-C.sub.6 H.sub.13  H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          C.sub.2 H.sub.4 OH  H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH--CH.sub.3                                                                         H OH H Cl                                                 |                                                                    OH                                                            i-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                               H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                         H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.2                                                  H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                                  H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                              H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.                    2                   H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CON(CH.sub.3).sub.2                                                                  H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.2                                                       H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CON(C.sub.2 H.sub.5).sub.2                                                           H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H                              H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  N          --CH.sub.2 --CH.sub.2 --NO                                                                        H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H                              H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H          --CH.sub.2 --CH.sub.2 --NN--CH.sub.3                                                              H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  n-C.sub.5 H.sub.11                                                                       n-C.sub.5 H.sub.11  H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13  H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7   H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9   H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH  H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub.2 --CH--CH.sub.3                                                                         H OH H Cl                                      | |                                                         OH         OH                                                            i-C.sub.4 H.sub.9                                                                  --CH.sub.3 C.sub.2 H.sub.4 OH  H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                               H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H                              H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H                              H OH H Cl                                 i-C.sub.4 H.sub.9                                                                  H                              H OH H Cl                                 i-C.sub.4 H.sub.9                   H OH H Cl                                 i-C.sub.4 H.sub.9                   H OH H Cl                                 i-C.sub.4 H.sub.9                   H OH H Cl                                 i-C.sub.4 H.sub.9                   H OH H Cl                                 i-C.sub.4 H.sub.9                   H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          H                   H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          CH.sub.3            H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          C.sub.2 H.sub.5     H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          n-C.sub.3 H.sub.7   H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          n-C.sub.4 H.sub.9   H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          i-C.sub. 3 H.sub.7  H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          i-C.sub.4 H.sub. 9  H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          n-C.sub.5 H.sub.11  H OH H Cl                                 sec.-C.sub. 4 H.sub.9                                                              H          n-C.sub. 6 H.sub.13 H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          C.sub.2 H.sub.4 OH  H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          --CH.sub.2 --CH--CH.sub.3                                                                         H OH H Cl                                                 |                                                                    OH                                                            sec.-C.sub.4 H.sub.9                                                               H          --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                               H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                                         H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.                                                   H OH H Cl                                 sec.-C.sub.4 H.sub. 9                                                              H          --CH.sub.2 --CH.sub.2 --N(C.sub.4 H.sub.9).sub.2                                                  H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(CH.sub.3).sub.2                                              H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          --CH.sub.2 --CH.sub.2 --CH.sub.2 --N(C.sub.2 H.sub.5).sub.                    2                   H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          --CH.sub.2 --CON(CH.sub.3).sub. 2                                                                 H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          --CH.sub.2 --CH.sub.2 --CON(CH.sub.3).sub.                                                        H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          --CH.sub.2 --CON(C.sub. 2 H.sub.5).sub.                                                           H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H                              H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          --CH.sub.2 --CH.sub.2 --NO                                                                        H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H                              H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H          --CH.sub.2 --CH.sub.2 --N--CH.sub.3                                                               H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               n-C.sub.5 H.sub. 11                                                                      n-C.sub.5 H.sub.11  H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               n-C.sub.6 H.sub.13                                                                       n-C.sub.6 H.sub.13  H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               i-C.sub.3 H.sub.7                                                                        i-C.sub.3 H.sub.7   H OH H Cl                                 sec.-C.sub.4 H.sub. 9                                                              i-C.sub.4 H.sub.9                                                                        i-C.sub.4 H.sub.9   H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               C.sub.2 H.sub.4 OH                                                                       C.sub.2 H.sub.4 OH  H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               --CH.sub.2 --CH--CH.sub.3                                                                --CH.sub. 2 --CH--CH.sub.3                                                                        H OH H Cl                                      | |                                                         OH         OH                                                            sec.-C.sub.4 H.sub.9                                                               --CH.sub.3 C.sub.2 H.sub.4 OH  H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                      --CH.sub.2 --CH.sub.2 --CH.sub.2 OH                                                               H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               --CH.sub.2 --C.sub.6 H.sub.5                                                             --CH.sub.2 --C.sub.6 H.sub.5                                                                      H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                  --CH.sub.2 --CH.sub.2 --C.sub.6 H.sub.5                                                           H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H                              H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H                              H OH H Cl                                 sec.-C.sub.4 H.sub.9                                                               H                              H OH H Cl                                 sec.-C.sub.4 H.sub.9                H OH H Cl                                 sec.-C.sub.4 H.sub.9                H OH H Cl                                 sec.-C.sub.4 H.sub.9                H OH H Cl                                 sec.-C.sub.4 H.sub.9                H OH H Cl                                 sec.-C.sub.4 H.sub.9                H OH H Cl                                 __________________________________________________________________________

Further examples of compounds to be prepared according to the inventionare the following substituted tetracyclines:

                                      TABLE VIa                                   __________________________________________________________________________    R.sub.1                                                                           R.sub.2        R.sub.3     R.sub.4                                                                         R.sub.5                                                                          R.sub.6                                                                         R.sub. 7                                __________________________________________________________________________    CH.sub.3                                                                          CH.sub.3       CH.sub.3    H OH H H                                       CH.sub.3                                                                          CH.sub.3       C.sub.2 H.sub.5                                                                           H OH H H                                       CH.sub.3                                                                          C.sub.2 H.sub.5                                                                              C.sub.2 H.sub.5                                                                           H OH H H                                       CH.sub.3                                                                          n-C.sub.3 H.sub.7                                                                            n-C.sub.3 H.sub.7                                                                         H OH H H                                       CH.sub.3                                                                          n-C.sub.4 H.sub.9                                                                            n-C.sub.4 H.sub.9                                                                         H OH H H                                       CH.sub.3                                                                          H              CH.sub.2 --COOH                                                                           H OH H H                                       CH.sub.3                                                                          H              CH.sub.2 --COOC.sub.2 H.sub.5                                                             H OH H H                                       CH.sub.3                                                                          H              CH.sub.3 --CH--COOH                                                                       H OH H H                                                          |                                                 CH.sub.3                                                                          H              CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                         H OH H H                                                          |                                                 CH.sub.3                                                                          H              --CH.sub.2 --CH.sub.2 --COOH                                                              H OH H H                                       CH.sub.3                                                                          H              --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                H OH H H                                       CH.sub.3                                                                          H              --(CH.sub.2).sub.4 --CH--COOH                                                             H OH H H                                                          |                                                                    NH.sub.2                                                   CH.sub.3                       H OH H H                                       CH.sub.3                       H OH H H                                       CH.sub.3                       H OH H H                                       CH.sub.3                       H OH H H                                       CH.sub.3                       H OH H H                                       CH.sub.3                       H OH H H                                       CH.sub.3                       H OH H H                                       C.sub.2 H.sub.5                                                                   CH.sub.3       CH.sub.3    H OH H H                                       C.sub.2 H.sub.5                                                                   CH.sub.3       C.sub.2 H.sub.5                                                                           H OH H H                                       C.sub.2 H.sub.5                                                                   C.sub.2 H.sub.5                                                                              C.sub.2 H.sub.5                                                                           H OH H H                                       C.sub.2 H.sub.5                                                                   n-C.sub.3 H.sub.7                                                                            n-C.sub.3 H.sub.7                                                                         H OH H H                                       C.sub.2 H.sub.5                                                                   n-C.sub.4 H.sub.9                                                                            n-C.sub.4 H.sub.9                                                                         H OH H H                                       C.sub.2 H.sub.5                                                                   H              CH.sub.2 --COOH                                                                           H OH H H                                       C.sub.2 H.sub.5                                                                   H              CH.sub.2 --COOC.sub.2 H.sub.5                                                             H OH H H                                       C.sub.2 H.sub.5                                                                   H              CH.sub.3 --CH--COOH                                                                       H OH H H                                                          |                                                 C.sub.2 H.sub.5                                                                   H              CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                         H OH H H                                       C.sub.2 H.sub.5                                                                   H              --CH.sub.2 --CH.sub.2 --COOH                                                              H OH H H                                       C.sub.2 H.sub.5                                                                   H              --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                H OH H H                                       C.sub.2 H.sub.5                                                                   H              --(CH.sub.2).sub.4 --CH--COOH                                                             H OH H H                                                          |                                                                    NH.sub.2                                                   C.sub.2 H.sub.5                H OH H H                                       C.sub.2 H.sub.5                H OH H H                                       C.sub.2 H.sub.5                H OH H H                                       C.sub.2 H.sub.5                H OH H H                                       C.sub.2 H.sub.5                H OH H H                                       C.sub.2 H.sub.5                H OH H H                                       C.sub.2 H.sub.5                H OH H H                                       n-C.sub.3 H.sub.7                                                                 CH.sub.3       CH.sub.3    H OH H H                                       n-C.sub.3 H.sub.7                                                                 CH.sub.3       C.sub.2 H.sub.5                                                                           H OH H H                                       n-C.sub.3 H.sub.7                                                                 C.sub.2 H.sub.5                                                                              C.sub.2 H.sub.5                                                                           H OH H H                                       n-C.sub.3 H.sub.7                                                                 n-C.sub.3 H.sub.7                                                                            n-C.sub.3 H.sub.7                                                                         H OH H H                                       n-C.sub.3 H.sub.7                                                                 n-C.sub.4 H.sub.9                                                                            n-C.sub.4 H.sub.9                                                                         H OH H H                                       n-C.sub.3 H.sub.7                                                                 H              CH.sub.2 --COOH                                                                           H OH H H                                       n-C.sub.3 H.sub.7                                                                 H              CH.sub.2 --COOC.sub.2 H.sub.5                                                             H OH H H                                       n-C.sub.3 H.sub.7                                                                 H              CH.sub.3 --CH--COOH                                                                       H OH H H                                                          |                                                 n-C.sub.3 H.sub.7                                                                 H              CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                         H OH H H                                                          |                                                 n-C.sub.3 H.sub.7                                                                 H              --CH.sub.2 --CH.sub.2 --COOH                                                              H OH H H                                       n-C.sub.3 H.sub.7                                                                 H              --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                H OH H H                                       n-C.sub.3 H.sub.7                                                                 H              --(CH.sub.2).sub.4 --CH--COOH                                                             H OH H H                                                          |                                                                    NH.sub.2                                                   n-C.sub.3 H.sub.7              H OH H H                                       n-C.sub.3 H.sub.7              H OH H H                                       n-C.sub.3 H.sub.7              H OH H H                                       n-C.sub.3 H.sub.7              H OH H H                                       n-C.sub.3 H.sub.7              H OH H H                                       n-C.sub.3 H.sub.7              H OH H H                                       n-C.sub.3 H.sub.7              H OH H H                                       n-C.sub.4 H.sub.9                                                                 CH.sub.3       CH.sub.3    H OH H H                                       n-C.sub.4 H.sub.9                                                                 CH.sub.3       C.sub.2 H.sub.5                                                                           H OH H H                                       n-C.sub.4 H.sub.9                                                                 C.sub.2 H.sub.5                                                                              C.sub.2 H.sub.5                                                                           H OH H H                                       n-C.sub.4 H.sub.9                                                                 n-C.sub.3 H.sub.7                                                                            n-C.sub.3 H.sub.7                                                                         H OH H H                                       n-C.sub.4 H.sub.9                                                                 n-C.sub.4 H.sub.9                                                                            n-C.sub.4 H.sub.9                                                                         H OH H H                                       n-C.sub.4 H.sub.9                                                                 H              CH.sub.2 --COOH                                                                           H OH H H                                       n-C.sub.4 H.sub.9                                                                 H              CH.sub.2 --COOC.sub.2 H.sub.5                                                             H OH H H                                       n-C.sub.4 H.sub.9                                                                 H              CH.sub.3 --CH--COOH                                                                       H OH H H                                                          |                                                 n-C.sub.4 H.sub.9                                                                 H              CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                         H OH H H                                                          |                                                 n-C.sub.4 H.sub.9                                                                 H              --CH.sub.2 --CH.sub.2 --COOH                                                              H OH H H                                       n-C.sub.4 H.sub.9                                                                 H              --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                H OH H H                                       n-C.sub.4 H.sub.9                                                                 H              --(CH.sub.2).sub.4 --CH--COOH                                                             H OH H H                                                          |                                                                    NH.sub.2                                                   n-C.sub.4 H.sub.9              H OH H H                                       n-C.sub.4 H.sub.9              H OH H H                                       n-C.sub.4 H.sub.9              H OH H H                                       n-C.sub.4 H.sub.9              H OH H H                                       n-C.sub.4 H.sub.9              H OH H H                                       n-C.sub.4 H.sub.9              H OH H H                                       n-C.sub.4 H.sub.9              H OH H H                                       __________________________________________________________________________

                                      TABLE VIb                                   __________________________________________________________________________    R.sub.1                                                                           R.sub.2      R.sub.3      R.sub.4                                                                         R.sub.5                                                                         R.sub.6                                                                         R.sub.7                                   __________________________________________________________________________    CH.sub.3                                                                          CH.sub.3     CH.sub.3     H H H --N(CH.sub.3).sub.2                       CH.sub.3                                                                          CH.sub.3     C.sub.2 H.sub.5                                                                            H H H --N(CH.sub.3).sub.2                       CH.sub.3                                                                          C.sub.2 H.sub.5                                                                            C.sub.2 H.sub.5                                                                            H H H --N(CH.sub.3).sub.2                       CH.sub.3                                                                          n-C.sub.3 H.sub.7                                                                          n-C.sub.3 H.sub.7                                                                          H H H --N(CH.sub.3).sub.2                       CH.sub.3                                                                          n-C.sub.4 H.sub.9                                                                          n-C.sub.4 H.sub.9                                                                          H H H --N(CH.sub.3).sub.2                       CH.sub.3                                                                          H            CH.sub.2 --COOH                                                                            H H H --N(CH.sub.3).sub.2                       CH.sub.3                                                                          H            CH.sub.2 --COOC.sub. 2 H.sub.5                                                             H H H --N(CH.sub.3).sub.2                       CH.sub.3                                                                          H            CH.sub.3 --CH--COOH                                                                        H H H --N(CH.sub.3).sub.2                                        |                                                   CH.sub.3                                                                          H            CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                          H H H --N(CH.sub.3).sub.2                                        |                                                   CH.sub.3                                                                          H            --CH.sub.2 --CH.sub.2 --COOH                                                               H H H --N(CH.sub.3).sub.2                       CH.sub.3                                                                          H            --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                 H H H --N(CH.sub.3).sub.2                       CH.sub.3                                                                          H            --(CH.sub.2).sub.4 --CH--COOH                                                              H H H --N(CH.sub. 3).sub.2                                       |                                                                    NH.sub.2                                                     CH.sub.3                      H H H --N(CH.sub.3).sub.2                       CH.sub.3                      H H H --N(CH.sub.3).sub.2                       CH.sub. 3                     H H H --N(CH.sub.3).sub.2                       CH.sub.3                      H H H --N(CH.sub.3).sub.2                       CH.sub. 3                     H H H --N(CH.sub.3).sub.2                       CH.sub.3                      H H H --N(CH.sub.3 ).sub.2                      CH.sub.3                      H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5                                                                   CH.sub.3     CH.sub.3     H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5                                                                   CH.sub.3     C.sub.2 H.sub.5                                                                            H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5                                                                   C.sub.2 H.sub.5                                                                            C.sub.2 H.sub.5                                                                            H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5                                                                   n-C.sub.3 H.sub.7                                                                          n-C.sub.3 H.sub.7                                                                          H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5                                                                   n-C.sub.4 H.sub.9                                                                          n-C.sub.4 H.sub.9                                                                          H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5                                                                   H            CH.sub.2 --COOH                                                                            H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5                                                                   H            CH.sub.2 --COOC.sub.2 H.sub.5                                                              H H H --N(CH.sub. 3).sub.2                      C.sub.2 H.sub.5                                                                   H            CH.sub.3 --CH--COOH                                                                        H H H --N(CH.sub.3).sub.2                                        |                                                   C.sub.2 H.sub.5                                                                   H            CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                          H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5  |-                                                      H            --CH.sub.2 --CH.sub.2 --COOH                                                               H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5                                                                   H            --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                 H H H --N(CH.sub.3 ).sub.2                      C.sub.2 H.sub.5                                                                   H            --(CH.sub.2).sub.4 --CH--COOH                                                              H H H --N(CH.sub.3).sub.2                                        |                                                                    NH.sub.2                                                     C.sub.2 H.sub.5               H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5               H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5               H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5               H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5               H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5               H H H --N(CH.sub.3).sub.2                       C.sub.2 H.sub.5               H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7                                                                 CH.sub.3     CH.sub.3     H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7                                                                 CH.sub.3     C.sub.2 H.sub.5                                                                            H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7                                                                 C.sub.2 H.sub.5                                                                            C.sub.2 H.sub.5                                                                            H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7                                                                 n-C.sub.3 H.sub.7                                                                          n-C.sub.3 H.sub.7                                                                          H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7                                                                 n-C.sub.4 H.sub.9                                                                          n-C.sub.4 H.sub.9                                                                          H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7                                                                 H            CH.sub.2 --COOH                                                                            H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7                                                                 H            CH.sub.2 --COOC.sub.2 H.sub.5                                                              H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7                                                                 H            CH.sub.3 --CH--COOH                                                                        H H H --N(CH.sub.3).sub.2                                        |                                                   n-C.sub.3 H.sub.7                                                                 H            CH.sub.CH--COOC.sub.2 H.sub.5                                                              H H H --N(CH.sub.3).sub.2                                        |                                                   n-C.sub.3 H.sub.7                                                                 H            --CH.sub.2 --CH.sub.2 --COOH                                                               H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7                                                                 H            --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                 H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7                                                                 H            --(CH.sub.2).sub.4 --CH--COOH                                                              H H H --N(CH.sub.3).sub.2                                        |                                                                    NH.sub.2                                                     n-C.sub.3 H.sub.7             H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7             H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7             H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7             H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7             H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7             H H H --N(CH.sub.3).sub.2                       n-C.sub.3 H.sub.7             H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9                                                                 CH.sub.3     CH.sub.3     H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9                                                                 CH.sub.3     C.sub.2 H.sub.5                                                                            H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9                                                                 C.sub.2 H.sub.5                                                                            C.sub.2 H.sub.5                                                                            H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9                                                                 n-C.sub.3 H.sub.7                                                                          n-C.sub.3 H.sub.7                                                                          H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9                                                                 n-C.sub.4 H.sub.9                                                                          n-C.sub.4 H.sub.9                                                                          H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9                                                                 H            CH.sub.2 --COOH                                                                            H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9                                                                 H            CH.sub.2 --COOC.sub.2 H.sub.5                                                              H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9                                                                 H            CH.sub.3 --CH--COOH                                                                        H H H --N(CH.sub.3).sub.2                                        |                                                   n-C.sub.4 H.sub.9                                                                 H            CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                          H H H --N(CH.sub.3).sub.2                                        |                                                   n-C.sub.4 H.sub.9                                                                 H            --CH.sub.2 --CH.sub.2 --COOH                                                               H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9                                                                 H            --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                 H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9                                                                 H            --(CH.sub.2).sub.4 --CH--COOH                                                              H H H --N(CH.sub.3).sub.2                                        |                                                                    NH.sub.2                                                     n-C.sub.4 H.sub.9             H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9             H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9             H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9             H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9             H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9             H H H --N(CH.sub.3).sub.2                       n-C.sub.4 H.sub.9             H H H --N(CH.sub.3).sub.2                       __________________________________________________________________________

                                      TABLE VIc                                   __________________________________________________________________________    R.sub.1                                                                           R.sub.2      R.sub.3      R.sub.4                                                                          R.sub.5                                                                         R.sub.6                                                                           R.sub.7                                __________________________________________________________________________    CH.sub.3                                                                          CH.sub.3     CH.sub.3     OH =CH.sub.2                                                                           H                                      CH.sub.3                                                                          CH.sub.3     C.sub.2 H.sub.5                                                                            OH =CH.sub.2                                                                           H                                      CH.sub.3                                                                          C.sub.2 H.sub.5                                                                            C.sub.2 H.sub.5                                                                            OH =CH.sub.2                                                                           H                                      CH.sub.3                                                                          n-C.sub.3 H.sub.7                                                                          n-C.sub.3 H.sub.7                                                                          OH =CH.sub.2                                                                           H                                      CH.sub.3                                                                          n-C.sub.4 H.sub.9                                                                          n-C.sub.4 H.sub.9                                                                          OH =CH.sub.2                                                                           H                                      CH.sub.3                                                                          H            CH.sub.2 --COOH                                                                            OH =CH.sub.2                                                                           H                                      CH.sub.3                                                                          H            CH.sub.2 --COOC.sub.2 H.sub.5                                                              OH =CH.sub.2                                                                           H                                      CH.sub.3                                                                          H            CH.sub.3 --CH--COOH                                                                        OH =CH.sub.2                                                                           H                                                       |                                                   CH.sub.3                                                                          H            CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                          OH =CH.sub.2                                                                           H                                                       |                                                   CH.sub.3                                                                          H            --CH.sub.2 --CH.sub.2 --COOH                                                               OH =CH.sub.2                                                                           H                                      CH.sub.3                                                                          H            --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                 OH =CH.sub.2                                                                           H                                      CH.sub.3                                                                          H            --(CH.sub.2).sub.4 --CH--COOH                                                              OH =CH.sub.2                                                                           H                                                       |                                                                    NH.sub.2                                                     CH.sub.3                      OH =CH.sub.2                                                                           H                                      CH.sub.3                      OH =CH.sub.2                                                                           H                                      CH.sub.3                      OH =CH.sub.2                                                                           H                                      CH.sub.3                      OH =CH.sub.2                                                                           H                                      CH.sub.3                      OH =CH.sub.2                                                                           H                                      CH.sub.3                      OH =CH.sub.2                                                                           H                                      CH.sub.3                      OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5                                                                   CH.sub.3     CH.sub.3     OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5                                                                   CH.sub.3     C.sub.2 H.sub.5                                                                            OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5                                                                   C.sub.2 H.sub.5                                                                            C.sub.2 H.sub.5                                                                            OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5                                                                   n-C.sub.3 H.sub.7                                                                          n-C.sub.3 H.sub.7                                                                          OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5                                                                   n-C.sub.4 H.sub.9                                                                          n-C.sub.4 H.sub.9                                                                          OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5                                                                   H            CH.sub.2 --COOH                                                                            OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5                                                                   H            CH.sub.2 --COOC.sub.2 H.sub.5                                                              OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5                                                                   H            CH.sub.3 --CH--COOH                                                                        OH =CH.sub.2                                                                           H                                                       |                                                   C.sub.2 H.sub.5                                                                   H            CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                          OH =CH.sub.2                                                                           H                                                       |                                                   C.sub.2 H.sub.5                                                                   H            --CH.sub.2 --CH.sub.2 --COOH                                                               OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5                                                                   H            --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                 OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5                                                                   H            --(CH.sub.2).sub.4 --CH--COOH                                                              OH =CH.sub.2                                                                           H                                                       |                                                                    NH.sub.2                                                     C.sub.2 H.sub.5               OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5               OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5               OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5               OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5               OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5               OH =CH.sub.2                                                                           H                                      C.sub.2 H.sub.5               OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7                                                                 CH.sub.3     CH.sub.3     OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7                                                                 CH.sub.3     C.sub.2 H.sub.5                                                                            OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7                                                                 C.sub.2 H.sub.5                                                                            C.sub.2 H.sub.5                                                                            OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7                                                                 n-C.sub.3 H.sub.7                                                                          n-C.sub.3 H.sub.7                                                                          OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7                                                                 n-C.sub.4 H.sub.9                                                                          n-C.sub.4 H.sub.9                                                                          OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7                                                                 H            CH.sub.2 --COOH                                                                            OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7                                                                 H            CH.sub.2 --COOC.sub.2 H.sub.5                                                              OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7                                                                 H            CH.sub.3 --CH--COOH                                                                        OH =CH.sub.2                                                                           H                                                       |                                                   n-C.sub.3 H.sub.7                                                                 H            CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                          OH =CH.sub.2                                                                           H                                                       |                                                   n-C.sub.3 H.sub.7                                                                 H            --CH.sub.2 --CH.sub.2 --COOH                                                               OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7                                                                 H            --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                 OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7                                                                 H            --(CH.sub.2).sub.4 --CH--COOH                                                              OH =CH.sub.2                                                                           H                                                       |                                                                    NH.sub.2                                                     n-C.sub.3 H.sub.7             OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7             OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7             OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7             OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7             OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7             OH =CH.sub.2                                                                           H                                      n-C.sub.3 H.sub.7             OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9                                                                 CH.sub.3     CH.sub.3     OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9                                                                 CH.sub.3     C.sub.2 H.sub.5                                                                            OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9                                                                 C.sub.2 H.sub.5                                                                            C.sub.2 H.sub.5                                                                            OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9                                                                 n-C.sub.3 H.sub.7                                                                          n-C.sub.3 H.sub.7                                                                          OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9                                                                 n-C.sub.4 H.sub.9                                                                          n-C.sub.4 H.sub.9                                                                          OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9                                                                 H            CH.sub.2 --COOH                                                                            OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9                                                                 H            CH.sub.2 --COOC.sub.2 H.sub.5                                                              OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9                                                                 H            CH.sub.3 --CH--COOH                                                                        OH =CH.sub.2                                                                           H                                                       |                                                   n-C.sub.4 H.sub.9                                                                 H            CH.sub.3 --CH--COOC.sub.2 H.sub.5                                                          OH =CH.sub.2                                                                           H                                                       |                                                   n-C.sub.4 H.sub.9                                                                 H            --CH.sub.2 --CH.sub.2 --COOH                                                               OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9                                                                 H            --CH.sub.2 --CH.sub.2 --COOC.sub.2 H.sub.5                                                 OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9                                                                 H            --(CH.sub.2).sub.4 --CH--COOH                                                              OH =CH.sub.2                                                                           H                                                       |                                                                    NH.sub.2                                                     n-C.sub.4 H.sub.9             OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9             OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9             OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9             OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9             OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9             OH =CH.sub.2                                                                           H                                      n-C.sub.4 H.sub.9             OH =CH.sub.2                                                                           H                                      __________________________________________________________________________

The following Examples illustrate the invention:

EXAMPLE 1 N-(1-ethoxycarbonyl-1-dimethylamino-methyl)-tetracycline

4.4 Grams of tetracycline base were dissolved in 100 ml of chloroformand 3.2 g of ethyl semiacetal of ethyl glyoxylate and 2 ml of liquifieddimethylamine were added. The mixture was refluxed for 3 hours,concentrated by evaporation in vacuo, and the residue was dissolved inabout 20 ml of ethyl acetate. Precipitation with diisopropyl ether,suction-filtration and drying at greatly reduced pressure at roomtemperature yieldedN-(1-ethoxycarbonyl-1-dimethylamino-methyl)-tetracycline which starteddecomposing at 130°C.

Yield: 3.5 grams, C₂₈ H₃₄ N₃ O₁₀ . H₂ O (590.6), Calculated: C 57.0 H6.2 N 7.1 found: C 57.0 H 6.9 N 7.3.

The same result was obtained using 2.2 g of ethyl glyoxylate.

The following compounds (Examples 2 to 8) were prepared in an alalogousmanner. All the melting points given are decomposition points.

The R_(f) -values were determined on thin-layer chromatography platesmanufactured by Messrs. E. Merck/Darmstadt, F.R.G. (cellulose/ 0.1Nhydrochloric acid). The R_(f) -values were generally higher than thoseof the starting tetracyclines.

EXAMPLE 2 N-(1-n-butoxycarbonyl-1-dimethylamino-methyl)-tetracycline

Melting point: 103°C; R_(f) -value = 0.78, C₃₀ H₃₉ N₃ O₁₀ . H₂ O(619.6), calculated: C 58.2 H 6.7 N 6.8 O 28.4, found: C 58.7 H 7.0 N6.1 O 27.9.

EXAMPLE 3 N-(1-ethoxycarbonyl-1-pyrrolidyl(1)-methyl)-tetracycline

Melting point: 157°C, C₃₀ H₃₇ N₃ O₁₀ (598.6), calculated: C 60.0 H 6.1 N7.0, found: C 59.6 H 6.9 N 7.3.

EXAMPLE 4 N-(1-n-butoxycarbonyl-1-pyrrolidyl(1)-methyl)-tetracycline

Melting point: 97°C; R_(f) -value = 0.81, C₃₂ H₄₁ N₃ O₁₀ . H₂ O (645.6),calculated: C 59.5 H 6.7 N 6.5, found: C 60.0 H 7.4 N 6.3.

EXAMPLE 5 N-(1-ethoxycarbonyl-1-piperidyl(1)-methyl)-tetracycline

Melting point: 130°C; R_(f) -value = 0.82, C₃₁ H₃₉ N₃ O₁₀ (613.7),calculated: C 60.7 H 6.4 N 6.9, found: C 60.5 H 6.9 N 7.1.

In the H¹ -NMR (in CDCl₃), this compound showed, besides other typicalabsorption values, a characteristical absorption at 5.1 ppm for ##EQU2##

EXAMPLE 6 N-(1-n-butoxycarbonyl-1-piperidyl(1)-methyl)-tetracycline

Melting point: 110°C; R_(f) -value = 0.70, C₃₃ H₄₃ N₃ O₁₀ . H₂ O(659.6), calculated: C 60.1 H 6.9 N 6.4 O 26.7, found: C 59.5 H 7.3 N5.8 O 27.6.

EXAMPLE 7 N-(1-ethoxycarbonyl-1-morpholinyl(4)-methyl)-tetracycline

Melting point: 135°-145°C "; R_(f) -value = 0.70, C₃₀ H₃₇ N₃ O₁₁ . H₂ O(633.6), calculated: C 56.8 H 6.2 N 6.6, found: C 56.8 H 6.5 N 6.6.

EXAMPLE 8N-[1-ethoxycarbonyl-1-(4-β-hydroxyethylpiperazyl(1)-methyl]-tetracycline

Melting point: 133°-137°C, C₃₂ H₄₂ N₄ O₁₁ . H₂ O (676.7), calculated: C56.8 H 6.7 N 8.3, found: C 56.8 H 7.0 N 8.7.

EXAMPLE 9 N-(1-ethoxycarbonyl-1-dimethylamino-methyl)-oxytetracycline

4 Grams of the ethyl semiacetal of ethyl glyoxylate and 2 ml ofliquified dimethylamine were dissolved in 100 ml of dimethylformamide,and after 15 minutes 4.6 g of oxytetracycline base were added. Thelimpid solution was stirred for 5 hours at room temperature undernitrogen and then concentrated by evaporation at greatly reducedpressure and at a maximum temperature of 50°C. The oily residue wasdissolved in about 30 ml of ethyl acetate, filtered and the reactionproduct was precipitated with diisopropyl ether.

Upon drying at room temperature under greatly reduced pressure, 2.5 g ofN-(1-ethoxycarbonyl-1-dimethylamino-methyl)-oxytetracycline wereobtained; decomposition point 105°C; R_(f) -value = 0.79.

In an analogous manner, the compounds indicated in Examples 10 to 13were prepared.

EXAMPLE 10 N-(1-n-butoxycarbonyl-1-dimethylamino-methyl)-oxytetracycline

Melting point: 105°-108°C; R_(f) -value = 0.76, C₃₀ H₃₉ N₃ O₁₁ . H₂ O(635.7), calculated: C 56.7 H 6.5 N 6.6, found: C 56.4 H 7.0 N 6.2.

EXAMPLE 11 N-(1-ethoxycarbonyl-1-pyrrolidyl(1)-methyl)-oxytetracycline

Melting point: 150°C, C₃₀ H₃₇ N₃ O₁₁ . H₂ O (633.7), calculated: C 57.0H 6.2 N 6.6, found: C 56.7 H 6.3 N 6.8.

EXAMPLE 12 N-(1-butoxycarbonyl-1-pyrrolidyl(1)-methyl)-oxytetracycline

Melting point: 86°-90°C, C₃₂ H₄₁ N₃ O₁₁ (643.7), calculated: C 59.7 H6.4 N 6.5, found: C 59.4 H 6.7 N 6.3.

EXAMPLE 13 N-(1-ethoxycarbonyl-1-piperidyl(1)-methyl)-oxytetracycline

Melting point: 160°C; R_(f) -value = 0.81, C₃₁ H₃₇ N₃ O₁₁ . H₂ O(645.7), calculated: C 57.7 H 6.1 N 6.5, found: C 57.6 H 6.7 N 6.4.

In the H¹ -NMR (in CDCl₃), the compound showed, besides other typicalabsorption values, a characteristical absorption at 5.1 ppm for ##EQU3##

EXAMPLE 14N-(1-ethoxycarbonyl-1-dimethylamino-methyl)-chlorotetracycline

1.5 Milliliters of dimethylamine and 2.2 g of ethyl semiacetal of ethylglyoxylate were successively dissolved in 75 ml of dimethylformamideand, after 1 hour, 4.6 g of 7-chlorotetracycline base were added. Themixture was then stirred for 4 hours at room temperature under nitrogen,concentrated by evaporation at greatly reduced pressure and at a maximumtemperature of 50°C, and the oily residue was dissolved indichloromethane. The reaction product was precipitated by adding thesolution dropwise to diisopropyl ether, the precipitate was filtered anddried at room temperature under greatly reduced pressure.

Yield: 4.5 g; decomposition point: 137°C, C₂₈ H₃₄ CIN₃ O₁₀ (608.1),calculated: C 55.3 H 5.6 N 6.9, found: C 55.3 H 6.3 N 7.2.

In the H¹ -NMR (in CDCl₃), the compound showed inter alia acharacteristical absorption at 5.4 ppm for ##EQU4## Examples 15 - 18were carried out in analogous manner.

EXAMPLE 15N-(1-n-butoxycarbonyl-1-dimethylamino-methyl)-chlorotetracycline

Melting point: 100°C, C₃₀ H₃₈ CIN₃ O₁₀ (636.1), calculated: C 56.6 H 6.0Cl 5.6 N 6.6, found: C 55.5 H 6.3 Cl 5.8 N 6.7.

EXAMPLE 16N-(1-ethoxycarbonyl-1-pyrrolidyl(1)-methyl)-chlorotetracycline

Melting point: 122°-127°C; R_(f) -value = 0.81, C₃₀ H₃₈ CIN₃ O₁₀(634.1), calculated: C 56.8 H 5.7 Cl 5.6 N 6.6, found: C 56.8 H 6.2 Cl5.7 N 7.3.

EXAMPLE 17N-(1-n-butoxycarbonyl-1-pyrrolidyl(1)-methyl)-chlorotetracycline

Melting point: 95°C; R_(f) -value = 0.75, C₃₂ H₄₀ CIN₃ O₁₀ (662.2),calculated: C 58.0 H 6.1 Cl 5.4 N 6.4, found: C 58.5 H 6.0 Cl 5.4 N 6.3.

EXAMPLE 18 N-(1-ethoxycarbonyl-1-piperidyl(1)-methyl)-chlorotetracycline

Melting point: 177°C C₃₁ H₃₈ CIN₃ O₁₀ . H₂ O (666.1) calculated: C 55.9H 6.0 N 6.3 found: C 56.1 H 6.6 N 6.9.

EXAMPLE 19N-(1-ethoxycarbonyl-1-dimethylamino-methyl)-7-chloro-6-desmethyl-tetracycline

1 Milliliter of liquified dimethylamine and 5 g of ethyl semiacetal ofethyl glyoxylate were dissolved successively in 100 ml ofdimethylformamide, and after 1 hour 4.7 g of7chloro-6-desmethyl-tetracycline base were added. The mixture was thenstirred for 3 hours at room temperature under nitrogen and thenconcentrated by evaporation under greatly reduced pressure at a maximumtemperature of 50°C; the residue was dissolved in about 30 ml of ethylacetate, andN-(1-ethoxycarbonyl-1-dimethylamino-methyl)-7-chloro-6-desmethyl-tetracyclinewas precipitated with diisopropyl ether.

Yield: 4.8 grams; decomposition point: 109°-114°C. In the H¹ -NMR (inCDCl₃), the compound showed inter alia a characteristical absorption at5.4 ppm for ##EQU5## The Examples 20 - 23 were carried out in ananalogous manner.

EXAMPLE 20N-(1-n-butoxycarbonyl-1-dimethylamino-methyl)-7-chloro-6-desmethyl-tetracycline

Melting point: 100°-105°C; R_(f) -value = 0.68, C₂₉ H₃₆ ClN₃ O₁₀(622.1), calculated: C 56.1 H 5.8 Cl 5.7 N 6.8, found: C 55.5 H 6.3 Cl5.8 N 6.1.

EXAMPLE 21N-(1-ethoxycarbonyl-1-pyrrolidyl(1)-methyl)-7-chloro-6-desmethyl-tetracycline

Melting point: 134°-137°C, C₂₉ H₃₄ CIN₃ O₁₀ (620.1), calculated: C 56.2H 5.5 Cl 5.7 N 6.8, found: C 55.4 H 6.1 Cl 5.4 N 6.5.

EXAMPLE 22N-(1-n-butoxycarbonyl-1-pyrrolidyl(1)-methyl)-7-chloro-6-desmethyl-tetracycline

Melting point: 102°C; R_(f) -value = 0.76, C₃₁ H₃₆ CIN₃ O₁₀ (648.1),calculated: C 57.4 H 5.0 Cl 5.5 N 6.5, found: C 57.8 H 6.3 Cl 5.1 N 6.6.

EXAMPLE 23N-(1-ethoxycarbonyl-1-piperidyl(1)-methyl)-7-chloro-6-desmethyl-tetracyclin

Melting point: 117°-119°C, C₃₀ H₃₆ CIN₃ O₁₀ (652.1), calculated: C 55.1H 5.8 Cl 5.4 N 6.4, found: C 54.9 H 5.8 Cl 5.8 N 5.7.

We claim:
 1. A 2-carboxamido-substituted tetracycline of the generalformula I ##SPC5##in which R₁ is lower, optionally branched alkyl, R₂and R₃ may be identical or different and each is hydrogen, optionallybranched alkyl of 1 to 6 carbon atoms which may carry one or moreidentical or different substituents selected from the group consistingof hydroxy, lower dialkylamino, lower dialkylcarbamoyl, loweralkoxycarbonyl, phenyl, a heterocyclic group, especially a 5- or6-membered ring which may include oxygen and/or nitrogen, and carboxyl,in this latter case the alkyl moiety may also carry amino; or cycloalkylof 5 to 7 carbon atoms, and in which R₂ and R₃ may also be closed toform a saturated or unsaturated 5- or 6-membered ring which may includenitrogen or oxygen and may carry one or more substituents selected fromthe group consisting of lower alkyl, lower hydroxyalkyl, lowercarboxyalkyl, hydroxyl or carboxyl, R₄ and R₅ may be identical ordifferent and each is hydrogen or hydroxy, R₆ is hydrogen or methyl, R₅and R₆ together are methylene, and R₇ is hydrogen, chlorine, bromine,dimethylamino or diethylamino.
 2. A compound of claim 1 which isN-(1-ethoxycarbonyl-1-dimethylamino-methyl)-tetracycline.
 3. A compoundof claim 1 which isN-(1-n-butoxycarbonyl-1-dimethylamino-methyl)-tetracycline.
 4. Acompound of claim 1 which isN-(1-ethoxycarbonyl-1-pyrrolidyl(1)-methyl)-tetracycline.
 5. A compoundof claim 1 which isN-(1-n-butoxycarbonyl-1-pyrrolidyl(1)-methyl)-tetracycline.
 6. Acompound of claim 1 which isN-(1-ethoxycarbonyl-1-piperidyl(1)-methyl)-tetracycline.
 7. A compoundof claim 1 which isN-(1-n-butoxycarbonyl-1-piperidyl(1)-methyl)-tetracycline.
 8. A compoundof claim 1 which isN-(1-ethoxycarbonyl-1-morpholinyl(4)-methyl)-tetracycline.
 9. A compoundof claim 1 which isN-[1-ethoxycarbonyl-1-(4-β-hydroxyethylpiperazyl(1))-methyl]-tetracycline.10. A compound of claim 1 which isN-(1-ethoxycarbonyl-1-dimethylamino-methyl)-oxytetracycline.
 11. Acompound of claim 1 which isN-(1-n-butoxycarbonyl-1-dimethylamino-methyl)-oxytetracycline.
 12. Acompound of claim 1 which isN-(1-ethoxycarbonyl-1-pyrrolidyl(1)-methyl)-oxytetracycline.
 13. Acompound of claim 1 which isN-(1-n-butoxycarbonyl-1-pyrrolidyl(1)-methyl)-oxytetracycline.
 14. Acompound of claim 1 which isN-(1-ethoxycarbonyl-1-piperidyl(1)-methyl)-oxytetracycline.
 15. Acompound of claim 1 which isN-(1-ethoxycarbonyl-1-dimethylamino-methyl)-chlorotetracycline.
 16. Acompound of claim 1 which isN-(1-n-butoxycarbonyl-1-dimethylamino-methyl)-chlorotetracycline.
 17. Acompound of claim 1 which isN-(1-ethoxycarbonyl-1-pyrrolidyl(1)-methyl)-chlorotetracycline.
 18. Acompound of claim 1 which isN-(1-n-butoxycarbonyl-1-pyrrolidyl(1)-methyl)-chlorotetracycline.
 19. Acompound of claim 1 which isN-(1-ethoxycarbonyl-1-piperidyl(1)-methyl)-chlorotetracycline.
 20. Acompound of claim 1 which isN-(1-ethoxycarbonyl-1-dimethylamino-methyl)-7-chloro-6-desmethyl-tetracycline.21. A compound of claim 1 which isN-(1-n-butoxycarbonyl-1-dimethylamino-methyl)-7-chloro-6-desmethyl-tetracycline.22. A compound of claim 1 which isN-(1-ethoxycarbonyl-1-pyrrolidyl(1)-methyl)-7-chloro-6-desmethyl-tetracycline.23. A compound of claim 1 which isN-(1-n-butoxycarbonyl-1-pyrrolidyl(1)-methyl)-7-chloro-6-desmethyl-tetracycline.24. A compound of claim 1 which isN-(1-ethoxycarbonyl-1-piperidyl(1)-methyl)-7-chloro-6-desmethyl-tetracycline.25. A pharmaceutical composition having antibacterial activity whichcomprises an effective amount of a compound of formula I as the activesubstance.